"SMURF2" Related Products

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Recombinant Human SMURF2, FLAG-tagged

Cat. No.: SMURF2-468H
Product Overview: Recombinant Human SMURF2 (amino-acids 130-end) was expressed in a Baculovirus infected Sf9 cell expression system with N-terminal FLAG tag, MW= 72 kDa.
Description: SMURF2 has been shown to interact with Mothers against decapentaplegic homolog 7, SCYE1, SMURF1, Mothers against decapentaplegic homolog 3, Ubiquitin C, Mothers against decapentaplegic homolog 1 and Mothers against decapentaplegic homolog 2.
Source: Sf9.
Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 100 μg/ml FLAG peptide, 20% glycerol, and 3 mM DTT.
Application: Useful in conjunction with E1 and E2 for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Purity: > 80%.
Stability: >6 months at -80°C.
Gene Name: SMURF2 SMAD specific E3 ubiquitin protein ligase 2 [ Homo sapiens ]
Synonyms: SMAD specific E3 ubiquitin protein ligase 2; MGC138150; DKFZp686F0270; SMURF2; E3 ubiquitin ligase SMURF2; EC 6.3.2.-; hSMURF2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2
Gene ID: 64750
mRNA Refseq: NM_022739
Protein Refseq: NP_073576
MIM: 605532
UniProt ID: Q9HAU4
Chromosome Location: 17q22-q23
Pathway: Endocytosis; TGF-beta signaling pathway; Ubiquitin mediated proteolysis; Signaling by BMP; Signaling by TGF beta
Function: acid-amino acid ligase activity; identical protein binding; ligase activity; ubiquitin-protein ligase activity

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