Recombinant Human TSTA3

• Cat.No.: TSTA3-30306TH
• Product Overview: Recombinant full length human TSTA3 protein, 36.9kDa.

Specification

• Description: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
• Source: E. coli
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Gene Information

• Gene Name: TSTA3 tissue specific transplantation antigen P35B [ Homo sapiens ]
• Official Symbol: TSTA3
• Synonyms: TSTA3; tissue specific transplantation antigen P35B; GDP-L-fucose synthase; FX; GDP L fucose synthase; P35B; SDR4E1; short chain dehydrogenase/reductase family 4E; member 1
• Gene ID: 7264
• mRNA Refseq: NM_003313
• Protein Refseq: NP_003304
• MIM: 137020
• Uniprot ID: Q13630
• Chromosome Location: 8q24.3
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: GDP-4-dehydro-D-rhamnose reductase activity; GDP-L-fucose synthase activity; coenzyme binding; electron carrier activity; isomerase activity