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Recombinant Human TXN, His-tagged

Cat.No.: TXN-31511TH
Product Overview: Recombinant full length Human Thioredoxin / TRX protein fused to a 6X His tag at the N terminus, Amino acids 1-105, molecular weight: 14 kDa;
Description: The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.
Conjugation: HIS
Source: E. coli
Biological activity: Specific activity is 7-10 A650/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: PBS, pH 7.4
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Store in the dark. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the thioredoxin family.Contains 1 thioredoxin domain.
Gene Name: TXN thioredoxin [ Homo sapiens ]
Official Symbol: TXN
Synonyms: TXN; thioredoxin; TRX;
Gene ID: 7295
mRNA Refseq: NM_001244938
Protein Refseq: NP_001231867
MIM: 187700
Uniprot ID: P10599
Chromosome Location: 9q31
Pathway: Folic Acid Network, organism-specific biosystem; Folic Acid Network, organism-specific biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
Function: electron carrier activity; peptide disulfide oxidoreductase activity; protein binding; protein disulfide oxidoreductase activity;

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