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Recombinant Human UROS, His-tagged

Cat.No. : UROS-31080TH
Product Overview : Recombinant full length protein, corresponding to amino acids 1-265 of Human UROS, with N terminal His tag; Predicted MWt 30 kDa.
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Description : The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunthers disease).
Conjugation : HIS
Source : E. coli
Tissue specificity : Ubiquitous.
Form : Lyophilised:Reconstitute with 148 μl aqua dest.
Storage buffer : Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEF LSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNN KTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEG ETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKA LKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASIT FFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARAL AAQGLPVSCTAESPTPQALATGIRKALQPHGCC
Sequence Similarities : Belongs to the uroporphyrinogen-III synthase family.
Gene Name : UROS uroporphyrinogen III synthase [ Homo sapiens ]
Official Symbol : UROS
Synonyms : UROS; uroporphyrinogen III synthase; uroporphyrinogen-III synthase; congenital erythropoietic porphyria;
Gene ID : 7390
mRNA Refseq : NM_000375
Protein Refseq : NP_000366
MIM : 606938
Uniprot ID : P10746
Chromosome Location : 10q25.2-q26.3
Pathway : Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem;
Function : cofactor binding; lyase activity; uroporphyrinogen-III synthase activity; uroporphyrinogen-III synthase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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