"UROS" Related Products

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Recombinant Human UROS, His-tagged

Cat.No.: UROS-31080TH
Product Overview: Recombinant full length protein, corresponding to amino acids 1-265 of Human UROS, with N terminal His tag; Predicted MWt 30 kDa.
Description: The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunthers disease).
Conjugation: HIS
Source: E. coli
Tissue specificity: Ubiquitous.
Form: Lyophilised:Reconstitute with 148 μl aqua dest.
Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEF LSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNN KTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEG ETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKA LKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASIT FFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARAL AAQGLPVSCTAESPTPQALATGIRKALQPHGCC
Sequence Similarities: Belongs to the uroporphyrinogen-III synthase family.
Gene Name: UROS uroporphyrinogen III synthase [ Homo sapiens ]
Official Symbol: UROS
Synonyms: UROS; uroporphyrinogen III synthase; uroporphyrinogen-III synthase; congenital erythropoietic porphyria;
Gene ID: 7390
mRNA Refseq: NM_000375
Protein Refseq: NP_000366
MIM: 606938
Uniprot ID: P10746
Chromosome Location: 10q25.2-q26.3
Pathway: Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem;
Function: cofactor binding; lyase activity; uroporphyrinogen-III synthase activity; uroporphyrinogen-III synthase activity;

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