Recombinant Human XCL1, His-tagged

• Cat.No.: XCL1-28843TH
• Product Overview: Recombinant full length human Lymphotactin with N terminal His tag; amino acids 22-114 , 12.5kDa.

Specification

• Description: This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 30% Glycerol, 0.2M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MVGSEVSDKR TCVSLTTQRL PVSRIKTYTI TEGSLRAVIF ITKRGLKVCA DPQATWVRDV VRSMDRKSNT RNNMIQTKPT GTQQSTNTAV TLTG
• Sequence Similarities: Belongs to the intercrine gamma family.

Gene Information

• Gene Name: XCL1 chemokine (C motif) ligand 1 [ Homo sapiens ]
• Official Symbol: XCL1
• Synonyms: XCL1; chemokine (C motif) ligand 1; LTN, SCYC1, small inducible cytokine subfamily C, member 1 (lymphotactin); lymphotactin; ATAC; LPTN; SCM 1; SCM 1a
• Gene ID: 6375
• mRNA Refseq: NM_002995
• Protein Refseq: NP_002986
• MIM: 600250
• Uniprot ID: P47992
• Chromosome Location: 1q24.2
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem
• Function: chemokine activity; chemokine receptor binding; chemokine receptor binding; protein homodimerization activity