"XRCC3" Related Products

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Recombinant Human XRCC3, T7 -tagged

Cat.No.: XRCC3-30133TH
Product Overview: Recombinant full length protein: Human XRCC3 protein fused to T7-tag.
Description: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Conjugation: T7
Source: E. coli
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: 0.002% Sodium AzideConstituents: 10mM Tris, 10mM DTT, 0.1% Triton X-100, pH 8.0
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Belongs to the RecA family. RAD51 subfamily.
Gene Name: XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 [ Homo sapiens ]
Official Symbol: XRCC3
Synonyms: XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; DNA repair protein XRCC3; RAD51 like;
Gene ID: 7517
mRNA Refseq: NM_001100118
Protein Refseq: NP_001093588
MIM: 600675
Uniprot ID: O43542
Chromosome Location: 14q32.3
Pathway: Fluoropyrimidine Activity, organism-specific biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function: ATP binding; DNA binding; DNA-dependent ATPase activity; nucleotide binding;

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