"Tnfrsf11b" Related Products


Recombinant Mouse Tnfrsf11b, Fc-His

Cat. No. : Tnfrsf11b-189M
Product Overview : Recombinant Mouse OPG (Glu22-Leu401) produced inNSO Cellswas fused to Human IgG1 (Pro100-Lys330) - 6xHis tag.
Description : Osteoprotegerin (OPG), also known as osteoclastogenesis inhibitory factor (OCIF) is a cytokine, which can inhibit osteoclast differentiation, activity, and survival. It is a member of the tumor necrosis factor (TNF) receptor superfamily. OPG may provide a pharmacological tool for osteoporotic and erosive bone disorders.
Molecular Weight : The predicted molecular weight of Recombinant Mouse OPG is Mr 70.9 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 100 kDa.
Source : NSO Cells.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Biological Activity : The biological activity of Mouse OPG was determined by its ability to inhibit TRAIL mediated cytotoxicity using L929 mouse fibrosarcoma cells treated with TRAIL. The expected ED50 for this effect is 25-50 ng/ml in the presence of 50 ng/ml of recombinant human TRAIL.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) [ Mus musculus ]
Synonyms : Tnfrsf11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin); Opg; TR1; OCIF; osteoprotegerin; osteoclastogenesis inhibitory factor; OPG
Gene ID : 18383
mRNA Refseq : NM_008764
Protein Refseq : NP_032790
UniProt ID : O08712
Chromosome Location : 15 D1
Pathway : Cytokine-cytokine receptor interaction
Function : protein binding; receptor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.