Recombinant Bovine Interferon-Alpha

• Cat.No.: IFN-a-62B
• Product Overview: Recombinant Bovine interferon-alpha was expressed inYeast.MW=19.0kDa (166aa).

Specification

• Cat. No.: IFN-a-62B
• Description: The IFN-α proteins are produced by leukocytes. They are mainly involved in innate immune response against viral infection. They come in 14 subtypes that are called IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21. These genes for these IFN-α molecules are found together in a cluster on chromosome 9. IFN-α is also made synthetically as medication. Types are: Pegylated interferon alfa-2a ; Pegylated interferon alfa-2b.
• Source: Yeast.
• Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
• Purification: Ion-exchange chromatography.
• Purity: >95% as visualized by SDS-PAGE analysis.
• Amino Acid Sequence: CHLPHTHSLA NRRVLMLLQQ LRRVSPSSCL QDRNDFEFLQ EALGGSQLQK AQAISVLHEV TQHTFQLFST EGSPATWDKS LLDKLRAALD QQLTDLQACL TQEEGLRGAP LLKEDSSLAV RKYFHRLTLY LQEKRHSPCA WEVVRAEVMR AFSSSTNLQE SFRRKD.
• Bioactivity: In testing.
• Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

Gene Information

• Gene Name: IFN-a interferon-alpha [ Bos taurus ]
• Synonyms: interferon-alpha; IFNaA; IFN-a; interferon alpha-A; interferon alpha A
• Gene ID: 515951
• mRNA Refseq: NM_001017411.1
• Protein Refseq: NP_001017411.1
• UniProt ID: P05007
• Chromosome Location: 8
• Pathway: Antigen processing and presentation; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Jak-STAT signaling pathway; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity; RIG-I-like receptor signaling pathway; Regulation of autophagy; Toll-like receptor signaling pathway
• Function: cytokine activity; cytokine receptor binding