"IGF2" Related Products


Recombinant Human Insulin-like Growth Factor 2 (Somatomedin A)

Cat. No. : IGF2-373H
Product Overview : Recombinant human Xeno-free pro-IGF-II is expressed inhuman 293 cellsas a monomeric glycoprotein with an apparent molecular mass of 25 kDa.
Description : Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. Glycosylation contributes to stability in cell growth media and other applications. IGF-II expressed in E. coli is typically 7.5 kDa and nonglycosylated.
Source : Human 293 cells.
Activity : 2 to 8 ng/mL ED50.
Purity : >95%.
Endotoxin : Endotoxin-free.
Purity Confirmation : The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
Activity Assay : The specific activity was determined by the dose-dependent stimulation of the proliferation of MCF-7 cells (human breast cancer cell line).
Pathways : Diabetes pathways
Gene Name : IGF2 insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ]
Synonyms : insulin-like growth factor 2 (somatomedin A);INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II;insulin-like growth factor type 2; putative insulin-like growth factor II associated protein;chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018
Gene ID : 3481
mRNA Refseq : NM_000612
Protein Refseq : NP_000603
MIM : 147470
UniProt ID : P01344
Chromosome Location : 11p15.5
Function : growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding

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