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Recombinant Rat TrkA, FC Chimera

Cat.No. : Ntrk1-589R
Product Overview : Recombinant Rat TrkA was expressed inNSOCells.The recombinant mature human Trk A/Fc is a disulfide-linked homodimeric protein, Based on N-terminal.
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  • Gene Information
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Cat. No. : Ntrk1-589R
Description : A DNA sequence encoding the signal peptide from human CD33 joined with the extracellular domain of human TrkA was fused to the Fc region of human IgG1 via a polypeptide linker.
Source : Mammalian cells
Purity : > 95%, as determined by SDS-PAGE and visualized by silver stain.
Endotoxin : < 1.0 EU per 1 μg of the enzyme as determined by the LAL method. Measured by its ability to inhibit NGF-induced proliferation of TF1 cells. The ED50 for this effect is typically 0.8-4 μg/mL in the presence of 10 ng/mL of rhNGF. The cell number is assessed in a fluorometric assay using a redox sensitive dye,
Format : Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution : It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 100 μg/mL.
Storage : Lyophilized samples are stable for up to six months at -20℃to -70℃. Upon reconstitution, this cytokine, in the presence of a carrier protein, can be stored under sterile conditions at 2 -8℃ for one month or at -20℃ to -70℃in a manual defrost freezer for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Gene Name : Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 [ Rattus norvegicus ]
Synonyms : Ntrk;neurotrophic tyrosine kinase, receptor, type 1;Trk; Ntrk1;trk;trk-A;p140-TrkA;trkA proto-oncogene receptor;slow nerve growth factor receptor;high affinity nerve growth factor receptor
Gene ID : 59109
mRNA Refseq : NM_021589
Protein Refseq : NP_067600
UniProt ID : P35739.1
Chromosome Location : 2q34
Pathway : Endocytosis;MAPK signaling pathway;Neurotrophin signaling pathway; Pathways in cancer; Thyroid cancer
Function : protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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