Recombinant Rat TrkA, FC Chimera
Cat.No. : | Ntrk1-589R |
Product Overview : | Recombinant Rat TrkA was expressed inNSOCells.The recombinant mature human Trk A/Fc is a disulfide-linked homodimeric protein, Based on N-terminal. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Ntrk1-589R |
Description : | A DNA sequence encoding the signal peptide from human CD33 joined with the extracellular domain of human TrkA was fused to the Fc region of human IgG1 via a polypeptide linker. |
Source : | Mammalian cells |
Purity : | > 95%, as determined by SDS-PAGE and visualized by silver stain. |
Endotoxin : | < 1.0 EU per 1 μg of the enzyme as determined by the LAL method. Measured by its ability to inhibit NGF-induced proliferation of TF1 cells. The ED50 for this effect is typically 0.8-4 μg/mL in the presence of 10 ng/mL of rhNGF. The cell number is assessed in a fluorometric assay using a redox sensitive dye, |
Format : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 100 μg/mL. |
Storage : | Lyophilized samples are stable for up to six months at -20℃to -70℃. Upon reconstitution, this cytokine, in the presence of a carrier protein, can be stored under sterile conditions at 2 -8℃ for one month or at -20℃ to -70℃in a manual defrost freezer for three months without detectable loss of activity. Avoid repeated freeze-thaw cycles. |
Gene Name : | Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 [ Rattus norvegicus ] |
Synonyms : | Ntrk;neurotrophic tyrosine kinase, receptor, type 1;Trk; Ntrk1;trk;trk-A;p140-TrkA;trkA proto-oncogene receptor;slow nerve growth factor receptor;high affinity nerve growth factor receptor |
Gene ID : | 59109 |
mRNA Refseq : | NM_021589 |
Protein Refseq : | NP_067600 |
UniProt ID : | P35739.1 |
Chromosome Location : | 2q34 |
Pathway : | Endocytosis;MAPK signaling pathway;Neurotrophin signaling pathway; Pathways in cancer; Thyroid cancer |
Function : | protein binding |
Products Types
◆ Recombinant Protein | ||
NTRK1-2030H | Recombinant Human NTRK1 Protein, Fc/His-tagged | +Inquiry |
NTRK1-155H | Active Recombinant Human NTRK1 protein(Met1-Pro382), His&hFc-tagged | +Inquiry |
NTRK1-415M | Active Recombinant Mouse NTRK1 protein(Met1-Gly420), His-tagged | +Inquiry |
Ntrk1-45R | Active Recombinant Rat Ntrk1 protein(Met1-Pro418), His-tagged | +Inquiry |
NTRK1-260H | Recombinant Active Human NTRK1 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
NTRK1-963CCL | Recombinant Canine NTRK1 cell lysate | +Inquiry |
NTRK1-1086MCL | Recombinant Mouse NTRK1 cell lysate | +Inquiry |
NTRK1-2147HCL | Recombinant Human NTRK1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1627 | TrkA Functional Assay Kit | +Inquiry |
Kit-1546 | U2OS TrkA Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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