"PDGFA" Related Products

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Recombinant Human Platelet-derived Growth Factor AA

Cat. No.: PDGFA-375H
Product Overview: Recombinant human Xeno-free PDGFaa is expressed inhuman 293 cellsas a mixture of pro-dimers, pro-mature and mature dimers with an apparent molecular mass of 35 to 45 kDa.
Description: Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. The cytokine is produced in a human cell expression system with serum free, chemically defined media.
Source: Human 293 cells.
Activity: 200 to 1000 ng/mL ED50.
Purity: >95%.
Endotoxin: Endotoxin-free.
Purity Confirmation: The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
Activity Assay: The specific activity was determined by the dose-dependent stimulation of the proliferation of 3T3 cells.
Pathways: Focal adhesion; Gap junction; Glioma; MAPK signaling pathway; Melanoma; Prostate cancer; Regulation of actin cytoskeleton; Hemostasis
Gene Name: PDGFA platelet-derived growth factor alpha polypeptide [ Homo sapiens ]
Synonyms: platelet-derived growth factor alpha polypeptide; PDGF1; PDGF-A; PDGFA; platelet-derived growth factor alpha; PDGF A-chain; platelet-derived growth factor alpha chain; platelet-derived growth factor alpha isoform 2 preproprotein; PDGF1; PDGF subunit A; Platelet-derived growth factor A chain; platelet-derived growth factor alpha polypeptide
Gene ID: 5154
mRNA Refseq: NM_002607
Protein Refseq: NP_002598
MIM: 173430
UniProt ID: P04085
Chromosome Location: 7p22
Function: cell surface binding; collagen binding; growth factor activity; platelet-derived growth factor binding; platelet-derived growth factor receptor binding; contributes_to platelet-derived growth factor receptor binding; platelet-derived growth factor receptor binding; protein heterodimerization activity; protein homodimerization activity

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