|Cat. No. :
|Product Overview :
||Recombinant human Xeno-free TGF beta 2 is expressed fromhuman 293 cellsas a mature disulfide-linked homodimer with apparent molecular mass of 25 kDa.
||Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. The cytokine is greater than 95% pure.
||Human 293 cells.
||0.1 to 0.5 ng/mL ED50.
|Purity Confirmation :
||The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
|Activity Assay :
||The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
||Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Renal cell carcinoma; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway