"TGFB2" Related Products


Recombinant Human Transforming Growth Factor, Beta 2

Cat. No. : TGFB2-377H
Product Overview : Recombinant human Xeno-free TGF beta 2 is expressed fromhuman 293 cellsas a mature disulfide-linked homodimer with apparent molecular mass of 25 kDa.
Description : Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. The cytokine is greater than 95% pure.
Source : Human 293 cells.
Activity : 0.1 to 0.5 ng/mL ED50.
Purity : >95%.
Endotoxin : Endotoxin-free.
Purity Confirmation : The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
Activity Assay : The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Pathways : Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Renal cell carcinoma; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway
Gene Name : TGFB2 transforming growth factor, beta 2 [ Homo sapiens ]
Synonyms : MGC116892; TGF-beta2; TGFB2; Transforming growth factor beta-2; TGF-beta-2; Glioblastoma-derived T-cell suppressor factor; G-TSF; BSC-1 cell growth inhibitor; Polyergin; Cetermin
Gene ID : 7042
mRNA Refseq : NM_001135599
Protein Refseq : NP_001129071
MIM : 190220
UniProt ID : P61812
Chromosome Location : 1q41
Function : beta-amyloid binding; cytokine activity; growth factor activity; protein heterodimerization activity; protein homodimerization activity; receptor signaling protein serine/threonine kinase activity; type II transforming growth factor beta receptor binding

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