Recombinant Human Heat Shock 22kDa Protein 8, His-tagged HSPB8-2025H

Recombinant Human Heat Shock 22kDa Protein 8, His-tagged

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Recombinant Human Heat Shock 22kDa Protein 8, His-tagged

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Cat. No. : HSPB8-2025H
Product Overview : Recombinant human HSPB8, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques, 23.7 kDa (216aa).
Description : Heat shock protein beta-8 (HSPB8), also known as HSP22, member of the small heat shock protein superfamily. HSPB8 is predominantly transcribed in skeletal muscle and heart. The chaperone-like activity is of great importance to the function of HSPB8 in various processes including proliferation, apoptosis and macroautophagy. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 10% glycerol.
Purity : > 95% by SDS - PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MADGQMPFSC HYPSRLRRDP FRDSPLSSRL LDDGFGMDPF PDDLTASWPD WALPRLSSAW PGTLRSGMVPRGPTATARFG VPAEGRTPPP FPGEPWKVCV NVHSFKPEEL MVKTKDGYVE VSGKHEEKQQ EGGIVSKNFT KKIQLPAEVD PVTVFASLSPEGLLIIEAPQ VPPYSTFGES SFNNELPQDS QEVTCT.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : HSPB8 heat shock 22kDa protein 8 [ Homo sapiens ]
Synonyms : heat shock 22kDa protein 8; H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; HSPB8; E2-induced gene 1; protein kinase H11; heat shock protein beta-8; heat shock 27kDa protein 8; small stress protein-like protein HSP22; HspB8; CRYAC; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22
Gene ID : 26353
mRNA Refseq : NM_014365
Protein Refseq : NP_055180
MIM : 608014
UniProt ID : Q9UJY1
Chromosome Location : 12q24.23
Function : protein serine/threonine kinase activity; identical protein binding

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