"NEIL2" Related Products

Recombinant Human Nei Endonuclease VIII-like 2 (E. coli)

Cat. No.: NEIL2-2042H
Product Overview: Recombinant human Neil2 was expressed inE. coli, 38kDa.
Description: Endonuclease VIII-like 2 is an enzyme that in humans is encoded by the NEIL2 gene. NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
Source: E. coli.
Purity: 90% by SDS PAGE and Coomassie blue staining.
Buffer Component: 20mM Tris-HCl, pH 7.5, 300mM NaCl, 10% glycerol.
Storage: Stable for 2 years at -70°C from date of shipment. Please aliquot to avoid repeated freezing and thawing.
Gene Name: NEIL2 nei endonuclease VIII-like 2 (E. coli) [ Homo sapiens ]
Synonyms: nei endonuclease VIII-like 2 (E. coli); NEH2; NEI2; MGC2832; MGC4505; FLJ31644; NEIL2; nei like 2; nei like 2 (E. coli); Nei-like 2; DNA-(apurinic or apyrimidinic site) lyase Neil2; DNA glycosylase/AP lyase Neil2;EC 3.2.2.-,EC 4.2.99.18
Gene ID: 252969
mRNA Refseq: NM_001135746
Protein Refseq: NP_001129218
MIM: 608933
UniProt ID: Q969S2
Chromosome Location: 8p23.1
Pathway: Base excision repair
Function: hydrolase activity, hydrolyzing N-glycosyl compounds; DNA-(apurinic or apyrimidinic site) lyase activity; damaged DNA binding; lyase activity; metal ion binding; microtubule binding; zinc ion binding

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