Recombinant Human PPP2R4
Cat.No. : | PPP2R4-589H |
Product Overview : | Recombinant Human PPP2R4 is expressed inE. coli. The molecular weight of the recombinant Human PPP2R4 is 65 kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PPP2R4-589H. |
Description : | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. PPP2R4 serves as a scaffolding molecule to coordinate the assembly of the catalytic (PP2AC, GLO132-001) and variable B subunits, generating functionally diverse heterotrimers of the phosphatase. The A subunit contains 15 tandemly-repeated HEAT sequences which may participate in its function as a scaffolding molecule. The A subunit also serves to regulate the substrate selectivity and allosterically modulates the enzymatic properties of PP2Ac, namely via its polycation response. |
Source : | E. coli. |
Purity : | >90% by SDS-PAGE apparent Mr ~ 65-kDa. |
Supplied : | 1 mg in 50 ml 50 mM Tris-HCl pH 7.0 buffer containing 14 mM b-mercaptoethanol, 1 mM benzamidine, 0.1 mM phenylmethanesulfonyl fluoride, 1 mM EDTA and 50% glycerol. |
Storage : | Maintain preparations in aliquots at -70℃. Avoid repeated thawing. |
Gene Name : | PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 [ Homo sapiens ] |
Synonyms : | protein phosphatase 2A activator, regulatory subunit 4; PPP2R4; PP2A; PR53; PTPA; MGC2184; PPP2R4; serine/threonine-protein phosphatase 2A regulatory subunit B"; PP2A, subunit B"; PP2A phosphatase activator; phosphotyrosyl phosphatase activator;protein phosphatase 2A, regulatory subunit B" (PR 53); PP2A subunit B" isoform PR53 |
Gene ID : | 5524 |
mRNA Refseq : | NM_021131 |
Protein Refseq : | NP_066954 |
MIM : | 600756 |
UniProt ID : | Q15257 |
Chromosome Location : | 9q34 |
Function : | ATP binding; ATPase activity; protein heterodimerization activity;protein homodimerization activity;protein phosphatase 2A binding IDA; protein phosphatase type 2A regulator activity; protein phosphatase type 2A regulator activity; receptor binding; protein tyrosine phosphatase activator activity |
Products Types
◆ Recombinant Protein | ||
PPP2R4-7037M | Recombinant Mouse PPP2R4 Protein, His (Fc)-Avi-tagged | +Inquiry |
PPP2R4-13260M | Recombinant Mouse PPP2R4 Protein | +Inquiry |
PPP2R4-878Z | Recombinant Zebrafish PPP2R4 | +Inquiry |
PPP2R4-3022C | Recombinant Chicken PPP2R4 | +Inquiry |
PPP2R4-27572TH | Recombinant Human PPP2R4, His-tagged | +Inquiry |
◆ Lysates | ||
PPP2R4-2919HCL | Recombinant Human PPP2R4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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