Recombinant Human TNFRSF10C, Fc-tagged

• Cat.No.: TNFRSF10C-2096H
• Product Overview: Recombinant Human TNFRSF10C along with Fc tag is expressed inHEK 293cells. The molecular weight of the recombinant human TNFRSF10C is 48 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-90 kDa.

Specification

• Cat. No.: TNFRSF10C-2096H
• Description: TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor that can inhibit TRAIL-induced apoptosis. TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.
• Source: HEK 293.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain [ Homo sapiens ]
• Synonyms: TNFRSF10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; LIT; DCR1; TRID; CD263; TRAILR3; MGC149501; MGC149502; tumor necrosis factor receptor superfamily, member 10c; TRAIL receptor 3; decoy receptor 1; TNF related TRAIL receptor; lymphocyte inhibitor of TRAIL; decoy without an intracellular domain; antagonist decoy receptor for TRAIL/Apo-2L; TNF related apoptosis-inducing ligand receptor 3; TRAIL-R3; CD263 antigen; TNF-related apoptosis-inducing ligand receptor 3; Trail receptor without an intracellular domain
• Gene ID: 8794
• mRNA Refseq: NM_003841
• Protein Refseq: NP_003832
• MIM: 603613
• UniProt ID: O14798
• Chromosome Location: 8p22-p21
• Pathway: Poptosis; Cytokine-cytokine receptor interaction; Natural killer cell mediated cytotoxicity
• Function: transmembrane receptor activity