"FYN" Related Products

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Recombinant Human FYN Oncogene Related To SRC, FGR, YES, His-tagged

Cat. No.: FYN-2128H
Product Overview: Recombinant full length human FynT produced ininsect cells is fused to a his-tag.
Description: Fyn, a Src family tyrosine kinase, is important for normal development and function of T lymphocytes. Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that in humans is encoded by the FYN gene.This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Source/Host: insect cells.
MW: 63 kDa.
Application: Kinetics and functional studies, phosphorylation of target substrates, drug screening.
Long Term Storage: -20°C.
Gene Name: FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ]
Synonyms: FYN oncogene related to SRC, FGR, YES; SLK; SYN; MGC45350; FYN; proto-oncogene tyrosine-protein kinase fyn; src-like kinase; Protooncogene Syn; OTTHUMP00000017917; c-syn protooncogene; src/yes-related novel; tyrosine kinase p59fyn(T); p59-Fyn; protein-tyrosine kinase fyn ; OKT3-induced calcium influx regulator; EC 2.7.10.2; OTTHUMP00000017915; OTTHUMP00000017914; src-like kinase
Gene ID: 2534
mRNA Refseq: NM_002037
Protein Refseq: NP_002028
MIM: 137025
UniProt ID: P06241
Chromosome Location: 6q21
Pathway: Adherens junction; Axon guidance; Fc epsilon RI signaling pathway; Focal adhesion; Natural killer cell mediated cytotoxicity; Pathogenic Escherichia coli infection; Prion diseases; T cell receptor signaling pathway
Function: non-membrane spanning protein tyrosine kinase activity; ATP binding; glycoprotein binding; identical protein binding; manganese ion binding; metal ion binding; nucleotide binding; transferase activity; tubulin binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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