"FYN" Related Products

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Recombinant Human FYN Oncogene Related To SRC, FGR, YES, His-tagged

Cat. No. : FYN-2128H
Product Overview : Recombinant full length human FynT produced ininsect cells is fused to a his-tag.
Description : Fyn, a Src family tyrosine kinase, is important for normal development and function of T lymphocytes. Proto-oncogene tyrosine-protein kinase Fyn is an enzyme that in humans is encoded by the FYN gene.This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.
Source/Host : insect cells.
MW : 63 kDa.
Application : Kinetics and functional studies, phosphorylation of target substrates, drug screening.
Long Term Storage : -20°C.
PDB rendering based on 1a0n. :

Gene Name : FYN FYN oncogene related to SRC, FGR, YES [ Homo sapiens ]
Synonyms : FYN oncogene related to SRC, FGR, YES; SLK; SYN; MGC45350; FYN; proto-oncogene tyrosine-protein kinase fyn; src-like kinase; Protooncogene Syn; OTTHUMP00000017917; c-syn protooncogene; src/yes-related novel; tyrosine kinase p59fyn(T); p59-Fyn; protein-tyrosine kinase fyn ; OKT3-induced calcium influx regulator; EC 2.7.10.2; OTTHUMP00000017915; OTTHUMP00000017914; src-like kinase
Gene ID : 2534
mRNA Refseq : NM_002037
Protein Refseq : NP_002028
MIM : 137025
UniProt ID : P06241
Chromosome Location : 6q21
Pathway : Adherens junction; Axon guidance; Fc epsilon RI signaling pathway; Focal adhesion; Natural killer cell mediated cytotoxicity; Pathogenic Escherichia coli infection; Prion diseases; T cell receptor signaling pathway
Function : non-membrane spanning protein tyrosine kinase activity; ATP binding; glycoprotein binding; identical protein binding; manganese ion binding; metal ion binding; nucleotide binding; transferase activity; tubulin binding

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