"GUCY1A3" Related Products


Recombinant Human Guanylate Cyclase 1, Soluble, Alpha 3, His-tagged

Cat. No.: GUCY1A3-627H
Product Overview: Recombinant Human Guanylate Cyclase 1, Soluble, Alpha 3 is produced inSf9 cellsfused at the C-terminus to a His-tag. MW= 70kDa-86kDa.
Description: Guanylate cyclase soluble subunit alpha-3 is an enzyme that in humans is encoded by the GUCY1A3 gene. Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.
Source: Sf9 cells.
Purity: ≥90% (SDS-PAGE).
Concentration: 0.4mg/ml.
Formulation: Liquid. In 40mM TEA, pH 7.4 containing 2mM DTT, 1mM MgCl2 and 30% glycerol.
Application: Biophysical and enzymatic studies and drug screening.
Specificity: ≥0.075µmol/mg/min.
Storage And Stability: -80°C. We do not recommend to store for longer periods after opening and thawing of the product. Avoid freeze/thaw cycles.
Gene Name: GUCY1A3 guanylate cyclase 1, soluble, alpha 3 [ Homo sapiens ]
Synonyms: GUCY1A3; guanylate cyclase 1, soluble, alpha 3; GUCA3; GC-SA3; GUC1A3; GUCSA3; GUCY1A1; guanylate cyclase soluble subunit alpha-3; GCS-alpha-1; GCS-alpha-3; GC-S-alpha-1; soluble guanylate cyclase large subunit; EC
Gene ID: 2982
mRNA Refseq: NM_000856
Protein Refseq: NP_000847
MIM: 139396
UniProt ID: Q02108
Chromosome Location: 4q31.3-q33; 4q31.1-q31.2
Pathway: Gap junction; Long-term depression; Purine metabolism; Vascular smooth muscle contraction
Function: GTP binding; guanylate cyclase activity; heme binding; ion binding; nucleotide binding; protein heterodimerization activity; receptor activity

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