Recombinant Mouse Tnfrsf22, Fc Chimera

• Cat.No.: Tnfrsf22-2112M
• Product Overview: Recombinant Mouse Tnfrsf22 was produced inHEK 293cells. The extracellular domain of mouse DcTRAIL-R2 (aa 1-170), of the long splice variant of mouse DcTRAIL-R2, is fused to the Fc portion of human IgG1. MW = 53kDa (SDS-PAGE).

Specification

• Cat. No.: Tnfrsf22-2112M
• Source: HEK 293.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Lyophilized. Contains PBS.
• Concentration: 1mg/ml after reconstitution.
• Biological Activity: Inhibits mouse soluble TRAIL-induced apoptosis assessed in human Jurkat T-lymphoma cells and human B cells myeloma (BJAB) in a concentration range of 50-500µg/ml.
• Endotoxin Content: Endotoxin content is <0.01ng endotoxin/µg purified protein as determined byLimulus amebocyte lysate (LAL) assay (BioWhittaker).
• Reconstitution: Reconstitute with 50µl sterile distilled water. Further dilutions should be made with medium containing 5% fetal calf serum or other carrier protein.
• Specificity: Binds mouse soluble TRAIL and less potently human soluble TRAIL in an ELISA assay.
• Application: Flow Cytometry: Cell surface staining of mouse TRAIL by FC in combination with PAb to human IgG.
• Stability: Stable for at least 6 months after receipt when stored at -20°C.

Gene Information

• Gene Name: Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 [ Mus musculus ]
• Synonyms: Tnfrsf22; tumor necrosis factor receptor superfamily, member 22; SOBa; Tnfrh2; Tnfrsf1al2; mDcTrailr2; 2810028K06Rik; C130035G06Rik; tumor necrosis factor receptor superfamily member 22; TNF receptor homolog 2; decoy TRAIL receptor 2; TNF receptor family member SOBa; tumor necrosis factor receptor p60 homolog 2; tumor necrosis factor receptor superfamily, member 1a-like 2
• Gene ID: 79202
• mRNA Refseq: NM_023680
• Protein Refseq: NP_076169
• UniProt ID: Q9ER62
• Chromosome Location: 7 F5; 7 69.57 cM
• Function: TRAIL binding; protein binding; receptor activity