"SOX2" Related Products

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Recombinant Human SRY (Sex Determining Region Y)-Box 2, His-tagged

Cat. No.: SOX2-2049H
Product Overview: Recombinant human SOX2 protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 23.1kDa (208aa).
Description: SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach.
Source: E.coli.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 200mM NaCl, 2mM DTT, 40% glycerol.
Purity: > 90% by SDS - PAGE.
Concentration: 0.25 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY LEHHHHHH.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: SOX2 SRY (sex determining region Y)-box 2 [ Homo sapiens ]
Synonyms: SOX2; SRY (sex determining region Y)-box 2; ANOP3; MCOPS3; MGC2413; Transcription factor SOX-2; SRY-related HMG-box gene 2; transcription factor SOX2; sex-determining region Y-box 2
Gene ID: 6657
mRNA Refseq: NM_003106
Protein Refseq: NP_003097
MIM: 184429
UniProt ID: P48431
Chromosome Location: 3q26.3-q27
Function: chromatin binding; protein binding; sequence-specific DNA binding; transcription factor activity

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