Recombinant Human SRY (Sex Determining Region Y)-Box 2, His-tagged
Cat.No. : | SOX2-2049H |
Product Overview : | Recombinant human SOX2 protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 23.1kDa (208aa). |
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Species : | Human |
Source : | E.coli |
Tag : | His |
ProteinLength : | 1-200 a.a. |
Description : | SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. This Protein is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 200mM NaCl, 2mM DTT, 40% glycerol. |
Purity : | > 90% by SDS - PAGE. |
Concentration : | 0.25 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY LEHHHHHH. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name | SOX2 SRY (sex determining region Y)-box 2 [ Homo sapiens ] |
Synonyms | SOX2; SRY (sex determining region Y)-box 2; ANOP3; MCOPS3; MGC2413; Transcription factor SOX-2; SRY-related HMG-box gene 2; transcription factor SOX2; sex-determining region Y-box 2 |
Gene ID | 6657 |
mRNA Refseq | NM_003106 |
Protein Refseq | NP_003097 |
MIM | 184429 |
UniProt ID | P48431 |
Chromosome Location | 3q26.3-q27 |
Function | chromatin binding; protein binding; sequence-specific DNA binding; transcription factor activity |
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Not For Human Consumption!
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