"TLR1" Related Products

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Recombinant Human TLR1, Fc Chimera

Cat. No.: TLR1-685H
Product Overview: Recombinant Human TLR1 isproduced in mouseNSO/1 cells. The extracellular domain of human TLR1 is fused to the Fc portion of human IgG1. MW=120kDa (SDS-PAGE).
Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.
Source: NSO cell.
Purity: ≥95% (SDS-PAGE).
Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
Concentration: 1mg/ml after reconstitution.
Formulation: Lyophilized. Contains PBS.
Reconstitution: Reconstitute with 50µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
Stability: Stable for at least 6 months after receipt when stored at -20°C.
Storage: Long term storage: -20°C, short term storage: +4°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
Gene Name: TLR1 toll-like receptor 1 [ Homo sapiens ]
Synonyms:
TLR1; toll-like receptor 1; TIL; CD281; rsc786; KIAA0012; MGC104956; MGC126311; MGC126312; TIL. LPRS5; DKFZp547I0610; DKFZp564I0682
Gene ID: 7096
mRNA Refseq: NM_003263
Protein Refseq: NP_003254
MIM: 601194
UniProt ID: Q15399
Chromosome Location: 4p14
Pathway: Toll-like receptor signaling pathway; Signaling in Immune system
Function: protein binding; receptor activity; transmembrane receptor activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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