"PDP1" Related Products

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Recombinant Human PDP1, His-tagged

Cat. No.: PDP1-698H
Product Overview: Recombinant Human PDP1 with a His tag is expressed inBacteriaand column-purified.
Description: PDH kinases (PDK"s) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK"s are present in an organ-dependent manner. In all cases, PDK"s are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH.
Source: Bacteria.
Storage: Store at -80°C.
Gene Name: PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 [ Homo sapiens ]
Synonyms: PDP1; pyruvate dehyrogenase phosphatase catalytic subunit 1; PDP 1; PDPC 1; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; protein phosphatase 2C, magnesium-dependent, catalytic subunit; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; pyruvate dehydrogenase phosphatase catalytic subunit 1; PDH; PDP; PDPC; PPM2C; FLJ32517; FLJ56179; MGC119646; EC 3.1.3.43
Gene ID: 54704
mRNA Refseq: NM_001161778
Protein Refseq: NP_001155250
MIM: 605993
UniProt ID: Q9P0J1
Chromosome Location: 8q22.1
Pathway: Integration of energy metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle
Function: [pyruvate dehydrogenase (lipoamide)] phosphatase activity; calcium ion binding; hydrolase activity; magnesium-dependent protein serine/threonine phosphatase activity; protein complex binding

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