Recombinant Human PDP1, His-tagged

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Recombinant Human PDP1, His-tagged

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Cat. No. : PDP1-698H
Product Overview : Recombinant Human PDP1 with a His tag is expressed inBacteriaand column-purified.
Description : PDH kinases (PDK"s) deactivate PDH by reversible phosphorylation. In humans and rodents, 4 PDK"s are present in an organ-dependent manner. In all cases, PDK"s are physically part of the PDH complex (binding via lipoyl domain 2 of E2), and they phosphorylate the E1 subunit at 3 specific serine residues. PDH phosphatases remove the phosphorylation and restore activity of PDH.
Source : Bacteria.
Storage : Store at -80°C.
Gene Name : PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 [ Homo sapiens ]
Synonyms : PDP1; pyruvate dehyrogenase phosphatase catalytic subunit 1; PDP 1; PDPC 1; [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; protein phosphatase 2C, magnesium-dependent, catalytic subunit; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; pyruvate dehydrogenase phosphatase catalytic subunit 1; PDH; PDP; PDPC; PPM2C; FLJ32517; FLJ56179; MGC119646; EC 3.1.3.43
Gene ID : 54704
mRNA Refseq : NM_001161778
Protein Refseq : NP_001155250
MIM : 605993
UniProt ID : Q9P0J1
Chromosome Location : 8q22.1
Pathway : Integration of energy metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle
Function : [pyruvate dehydrogenase (lipoamide)] phosphatase activity; calcium ion binding; hydrolase activity; magnesium-dependent protein serine/threonine phosphatase activity; protein complex binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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