"ACE" Related Products


Recombinant Human ACE, His-tagged

Cat. No. : ACE-744H
Product Overview : Recombinant human ACE ectodomain (amino acids 30-1261) fused at the C-terminus to a His•Tag sequence and expressed inNSO cells. By SDS-PAGE, the apparent molecular weight of the glycosylated protein appears larger to be than 120 kDa under both reducing and non-reducing conditions.
Description : ACE is a zinc metallopeptidase that cleaves the C-terminal dipeptide from angiotensin I to produce the potent vasopressor octapeptide angiotensin II. ACE gene polymorphism has been a recent topic in Alzheimer"s disease studies. ACE is a type I membrane protein and exists in two isoforms, somatic and germinal.
Source : NSO cells.
Purity : ≥95% by SDS-PAGE.
Form : Liquid.In 75 mM NaCl, 12.5 mM Tris, 500 nM ZnCl2, 40% glycerol, pH 7.5. Please refer to vial label for lot-specific concentration.
Endotoxins : ≤1.0 EU/µg ACE.
Specific Activity : ≥1 unit/µg protein.
Unit Definition : One unit is defined as the amount of enzyme that will cleave 1 nmol MCA-RPPGFSAFK(DNP)-OH per min at 25°C, pH 6.5.
Toxicity : Standard Handling(MSDS available upon request).
Storage : ≤ -70℃. Avoid freeze/thaw. Following initial thaw, aliquot and freeze (-70°C).
Gene Name : ACE angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 [ Homo sapiens ]
Synonyms : ACE; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; DCP; ACE1; DCP1; CD143; MVCD3; MGC26566; angiotensin-converting enzyme; kininase II; peptidase P; CD143 antigentesticular ECA; carboxycathepsin; dipeptidyl carboxypeptidase 1; dipeptidyl carboxypeptidase I; angiotensin converting enzyme, somatic isoform; EC; Angiotensin-converting enzyme, soluble form
Gene ID : 1636
mRNA Refseq : NM_000789
Protein Refseq : NP_000780
MIM : 106180
UniProt ID : P12821
Chromosome Location : 17q23.3
Pathway : Chagas disease; Hypertrophic cardiomyopathy (HCM); Renin-angiotensin system
Function : actin binding; bradykinin receptor binding; carboxypeptidase activity; chloride ion binding; drug binding; metal ion binding; metallopeptidase activity; peptidase activity; peptide binding; peptidyl-dipeptidase activity; protein binding; zinc ion binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.