"FURIN" Related Products

Recombinant Human Furin (Paired Basic Amino Acid Cleaving Enzyme)

Cat. No.: FURIN-755H
Product Overview: Recombinant human furin was expressed in vaccinia virus (VV:hFUR713t) infectedBSC-40 cells. MW = 81 kDa.
Description: Furin is a membrane-associated, calcium-dependent, serine protease that belongs to the subtilisin-like pro-hormone convertase (PC) family. Members of this family cleave pro-hormones, neuropeptide precursors, some viral proteins, and bacterial toxins. The preparation was subjected to UV irradiation for 5 minutes to inactivate any residual virus.
Source: BSC-40 cells.
Form: Liquid. In 20 mM Bis-Tris buffer, 1 mg/ml BSA, pH 7.0.
Unit Definition: One unit is defined as the amount of furin that will cleave 1.0 pmol AMC from the substrate pGlu-Arg-Thr-Lys-Arg-AMC per min at 30°C, pH 7.5.
Toxicity: Standard Handling (MSDS available upon request).
Storage: ≤ -70℃. Avoid freeze/thaw. Following initial thaw, aliquot and freeze (-70℃).
Gene Name: FURIN furin (paired basic amino acid cleaving enzyme) [ Homo sapiens ]
Synonyms: FURIN; furin (paired basic amino acid cleaving enzyme); FUR; PACE; SPC1; PCSK3; FES upstream region; dibasic processing enzyme; dibasic-processing enzyme; furin, membrane associated receptor protein; proprotein convertase subtilisin/kexin type 3; paired basic amino acid residue-cleaving enzyme; EC; paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein)
Gene ID: 5045
mRNA Refseq: NM_002569
Protein Refseq: NP_002560
MIM: 136950
UniProt ID: P09958
Chromosome Location: 15q26.1
Pathway: Metabolism of proteins; Signaling by Notch; Signaling by PDGF; Signaling by TGF beta; Signalling by NGF
Function: endopeptidase activity; metal ion binding; nerve growth factor binding; peptidase activity; peptide binding; protease binding; protein binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.