"FURIN" Related Products

Recombinant Human Furin (Paired Basic Amino Acid Cleaving Enzyme)

Cat. No.: FURIN-755H
Product Overview: Recombinant human furin was expressed in vaccinia virus (VV:hFUR713t) infectedBSC-40 cells. MW = 81 kDa.
Description: Furin is a membrane-associated, calcium-dependent, serine protease that belongs to the subtilisin-like pro-hormone convertase (PC) family. Members of this family cleave pro-hormones, neuropeptide precursors, some viral proteins, and bacterial toxins. The preparation was subjected to UV irradiation for 5 minutes to inactivate any residual virus.
Source: BSC-40 cells.
Form: Liquid. In 20 mM Bis-Tris buffer, 1 mg/ml BSA, pH 7.0.
Unit Definition: One unit is defined as the amount of furin that will cleave 1.0 pmol AMC from the substrate pGlu-Arg-Thr-Lys-Arg-AMC per min at 30°C, pH 7.5.
Toxicity: Standard Handling (MSDS available upon request).
Storage: ≤ -70℃. Avoid freeze/thaw. Following initial thaw, aliquot and freeze (-70℃).
Gene Name: FURIN furin (paired basic amino acid cleaving enzyme) [ Homo sapiens ]
Synonyms: FURIN; furin (paired basic amino acid cleaving enzyme); FUR; PACE; SPC1; PCSK3; FES upstream region; dibasic processing enzyme; dibasic-processing enzyme; furin, membrane associated receptor protein; proprotein convertase subtilisin/kexin type 3; paired basic amino acid residue-cleaving enzyme; EC 3.4.21.75; paired basic amino acid cleaving enzyme (furin, membrane associated receptor protein)
Gene ID: 5045
mRNA Refseq: NM_002569
Protein Refseq: NP_002560
MIM: 136950
UniProt ID: P09958
Chromosome Location: 15q26.1
Pathway: Metabolism of proteins; Signaling by Notch; Signaling by PDGF; Signaling by TGF beta; Signalling by NGF
Function: endopeptidase activity; metal ion binding; nerve growth factor binding; peptidase activity; peptide binding; protease binding; protein binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.