Recombinant Human N-myc Downstream Regulated 1, T7-tagged

• Cat.No.: NDRG1-2947H
• Product Overview: Recombinant Human NDRG1 was produced inE.coliwith a T7 tag at N-terminus. MW = 42863 Da (1-394 aa).

Specification

• Cat. No.: NDRG1-2947H
• Description: N-myc downstream regulated gene (NDRG)-1 is one of 4 members of the NDRG α/β-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease.
• Source: E.coli.
• Form: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT.
• Purity: 95%.
• Applications: MS. SDS.

Gene Information

• Gene Name: NDRG1 N-myc downstream regulated 1 [ Homo sapiens ]
• Synonyms: NDRG1; N-myc downstream regulated 1; GC4; RTP; DRG1; NDR1; NMSL; TDD5; CAP43; CMT4D; HMSNL; RIT42; TARG1; PROXY1; protein regulated by oxygen-1; tunicamycin-responsive protein; differentiation-related gene 1 protein; nickel-specific induction protein Cap43; reducing agents and tunicamycin-responsive protein; DRG-1; DRG1; Protein NDRG1; N-myc downstream-regulated gene 1 protein; Rit42
• Gene ID: 10397
• mRNA Refseq: NM_001135242
• Protein Refseq: NP_001128714
• MIM: 605262
• UniProt ID: Q92597
• Chromosome Location: 8q24
• Function: protein binding