"TSPO" Related Products

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Recombinant Human TSPO, T7-tagged

Cat. No.: TSPO1-2961H
Product Overview: Recombinant Human TSPO (1-102 aa) is expressed inE.Coliwith a T7 tag at N-terminus.
Description: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Source: E.Coli.
MW: 16107 Da.
Purity: 95%.
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
Application: MS. SDS.
Gene Name: TSPO translocator protein (18kDa) [ Homo sapiens ]
Synonyms: TSPO; translocator protein (18kDa); OTTHUMP00000198251; benzodiazepine peripheral binding site; mitochondrial benzodiazepine receptor; peripheral benzodiazepine receptor; peripheral-type benzodiazepine receptor; translocator protein; DBI; IBP; MBR; PBR; PBS; BPBS; BZRP; PKBS; PTBR; mDRC; pk18
Gene ID: 706
mRNA Refseq: NM_000714
Protein Refseq: NP_000705
MIM: 109610
UniProt ID: P30536
Chromosome Location: 22q13.31
Pathway: Neuroactive ligand-receptor interaction
Function: benzodiazepine receptor activity; cholesterol binding; receptor activity

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