Recombinant Human RFC3, T7-tagged

• Cat.No.: RFC3-2980H
• Product Overview: Recombinant Human RFC3 (1-356 aa) is expressed inE.Coliwith a T7 tag at N-terminus.

Specification

• Cat. No.: RFC3-2980H
• Description: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kDa. This gene encodes the 38 kDa subunit. This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36, 37, and 40 kDa subunits.
• Source: E.Coli.
• MW: 40556 Da.
• Purity: 95%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
• Application: MS. SDS.

Gene Information

• Gene Name: RFC3 replication factor C (activator 1) 3, 38kDa [ Homo sapiens ]
• Synonyms: RFC3;replication factor C (activator 1) 3, 38kDa; A1 38 kDa subunit; RF-C 38 kDa subunit; RFC, 38 kD subunit; activator 1 38 kDa subunit; activator 1 subunit 3; replication factor C 38 kDa subunit; replication factor C subunit 3; MGC5276; RFC38
• Gene ID: 5983
• mRNA Refseq: NM_002915
• Protein Refseq: NP_002906
• MIM: 600405
• UniProt ID: P40938
• Chromosome Location: 13q13.2
• Pathway: DNA replication; Mismatch repair; Cell Cycle Checkpoints; Chromosome Maintenance; DNA Replication
• Function: ATP binding; contributes_to ATPase activity; DNA clamp loader activity; protein binding