Recombinant Human ADP-ribosylation Factor 6, His-tagged ARF6-3369H

Recombinant Human ADP-ribosylation Factor 6, His-tagged

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Recombinant Human ADP-ribosylation Factor 6, His-tagged

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Cat. No. : ARF6-3369H
Product Overview : Recombinant human ARF6 protein , fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 22.2 kDa (195aa).
Description : ADP-ribosylation factor 6, also known as ARF6, is a member of the ADP ribosylation factor family of GTP-binding proteins. It is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. Additionally, ARF6 play a central role in maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D.
Source : E.coli.
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 0.2mM PMSF.
Purity : > 95% by SDS - PAGE.
Concentration : 1.0 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MGKVLSKIFG NKEMRILMLG LDAAGKTTIL YKL KLGQSVT TIPTVGFNVE TVTYKNVKFN VWDVGGQDKIRPLWRHYYTG TQGLIF VV DC ADRDRIDEAR QELHRIINDR EMRDAIILIF ANKQDLPDAM KPHEIQEKLG LTRIRDRNWY VQPSCATSGDGLYEGLTWLT SNYKS.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Fuction : GTP binding; GTPase activity; nucleotide binding; protein binding; thioesterase binding
Pathways : Endocytosis; Fc gamma R-mediated phagocytosis
PDB rendering based on 1e0s. :

Gene Name : ARF6 ADP-ribosylation factor 6 [ Homo sapiens ]
Synonyms : ADP-ribosylation factor 6; DKFZp564M0264; ARF6
Gene ID : 382
mRNA Refseq : NM_001663
Protein Refseq : NP_001654
MIM : 600464
UniProt ID : P62330
Chromosome Location : 14q21.3

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