Recombinant Canine Interleukin 8 IL8-245C

Recombinant Canine Interleukin 8

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Recombinant Canine Interleukin 8

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Cat. No. : IL8-245C
Product Overview : Recombinant Canine IL8 was expressed inYeast. MW= 8.6 kDa (74 aa).
Description : Interleukin-8 (IL-8) is a chemokine, a member of the cytokine family that displays chemotactic activity for specific types of leukocytes. It is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8/IL-8 in response to a wide variety of pro-inflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses.
Source : Yeast.
Formulation/ Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification : Ion-exchange chromatography.
Purity : >95% as visualized by SDS-PAGE analysis.
Amino Acid Sequence : VSSELRCQCI KTHSTPFHPK YIKELRVIDS GPHCENSEII VKLFNGNEVC LDPKEKWVQK VVQIFLKKAE KQDP.
Bioactivity : In testing.
Stability And Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
PDB rendering based on 1IL8. :

Gene Name : IL8 interleukin 8 [ Canis lupus familiaris ]
Synonyms : interleukin 8; IL8; IL-8; interleukin-8; C-X-C motif chemokine 8
Gene ID : 403850
mRNA Refseq : NM_001003200.1
Protein Refseq : NP_001003200.1
UniProt ID : P41324
Chromosome Location : 13
Pathway : Bladder cancer; Chemokine signaling pathway; Cytokine-cytokine receptor interaction; NOD-like receptor signaling pathway; Pathways in cancer; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway

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