"IL8" Related Products


Recombinant Canine Interleukin 8

Cat. No.: IL8-245C
Product Overview: Recombinant Canine IL8 was expressed inYeast. MW= 8.6 kDa (74 aa).
Description: Interleukin-8 (IL-8) is a chemokine, a member of the cytokine family that displays chemotactic activity for specific types of leukocytes. It is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8/IL-8 in response to a wide variety of pro-inflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses.
Source: Yeast.
Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification: Ion-exchange chromatography.
Purity: >95% as visualized by SDS-PAGE analysis.
Bioactivity: In testing.
Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name: IL8 interleukin 8 [ Canis lupus familiaris ]
Synonyms: interleukin 8; IL8; IL-8; interleukin-8; C-X-C motif chemokine 8
Gene ID: 403850
mRNA Refseq: NM_001003200.1
Protein Refseq: NP_001003200.1
UniProt ID: P41324
Chromosome Location: 13
Pathway: Bladder cancer; Chemokine signaling pathway; Cytokine-cytokine receptor interaction; NOD-like receptor signaling pathway; Pathways in cancer; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway

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