Recombinant Canine Interleukin 8


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Recombinant Canine Interleukin 8

IL8 Related Products

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Cat. No. : IL8-245C
Product Overview : Recombinant Canine IL8 was expressed inYeast. MW= 8.6 kDa (74 aa).
Description : Interleukin-8 (IL-8) is a chemokine, a member of the cytokine family that displays chemotactic activity for specific types of leukocytes. It is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8/IL-8 in response to a wide variety of pro-inflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses.
Source : Yeast.
Formulation/ Reconstitution : Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification : Ion-exchange chromatography.
Purity : >95% as visualized by SDS-PAGE analysis.
Bioactivity : In testing.
Stability And Storage : Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
PDB rendering based on 1IL8. :

Gene Name : IL8 interleukin 8 [ Canis lupus familiaris ]
Synonyms : interleukin 8; IL8; IL-8; interleukin-8; C-X-C motif chemokine 8
Gene ID : 403850
mRNA Refseq : NM_001003200.1
Protein Refseq : NP_001003200.1
UniProt ID : P41324
Chromosome Location : 13
Pathway : Bladder cancer; Chemokine signaling pathway; Cytokine-cytokine receptor interaction; NOD-like receptor signaling pathway; Pathways in cancer; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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