Expand
| Cat. No.: | Trem2-3276M |
| Product Overview: | Recombinant Mouse TREM2 protein (Met 1-Ser 174), fused with the His tag at the N-terminus, was expressed inHuman Cells. |
| Description: | Triggering receptor expressed on myeloid cells 2 (TREM2) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the basal ganglia, corpus callosum, medulla oblongata and spinal cord, and microglial cells are the major TREM2-producing cell type in the central nervous system (CNS). TREM2 may play a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. |
| Source: | Human Cells. |
| Molecular Mass: | The secreted recombinant human TREM2 comprises 167 amino acids with a predicted molecular mass of 18.9 kDa. As a result of glycosylation, the apparent molecular mass of rhTREM2 is approximately 30-40 kDa band in SDS-PAGE under reducing conditions. |
| Predicted N Terminal: | His 19. |
| Purity: | > 90 % as determined by SDS-PAGE. |
| Formulation: | Lyophilized from sterile PBS , pH 7.4 |
| Endotoxin: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Reconstitution: | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
| Storage And Stability: | Samples are stable for up to twelve months from date of receipt at -700C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Gene Name: | TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens ] |
| Synonyms: | TREM2; triggering receptor expressed on myeloid cells 2; OTTHUMP00000016369; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; TREM-2; Trem2a; Trem2b; Trem2c |
| Gene ID: | 54209 |
| mRNA Refseq: | NM_018965 |
| Protein Refseq: | NP_061838 |
| MIM: | 605086 |
| UniProt ID: | Q9NZC2 |
| Chromosome Location: | 6p21.1 |
| Pathway: | Axon guidance |
| Function: | receptor activity |
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Download Datasheet
See All Trem2 Products
Download Datasheet