Recombinant Mouse Trem2, His-tagged

• Cat.No.: Trem2-3276M
• Product Overview: Recombinant Mouse TREM2 protein (Met 1-Pro 168), fused with the His tag at the N-terminus, was expressed inHuman Cells.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4
• Molecular Mass: The recombinant mouse TREM2 consists of 161 amino acids with the predicted molecular mass of 18 kDa. As a result of glycosylation, the apparent molecular mass of rmTREM2 is approximately 30-40 kDa in SDS-PAGE under reducing conditions.
• Protein Length: Met 1-Pro 168
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Publication:
  TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance (2016)

Gene Information

• Gene Name: Trem2 triggering receptor expressed on myeloid cells 2 [ Mus musculus ]
• Official Symbol: Trem2
• Synonyms: TREM2; triggering receptor expressed on myeloid cells 2; TREM-2; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; triggering receptor expressed on myeloid cells 2b; triggering receptor expressed on myeloid cells 2c; Trem2a; Trem2b; Trem2c
• Gene ID: 83433
• mRNA Refseq: NM_031254
• Protein Refseq: NP_112544