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Recombinant Human Gremlin 2, His-tagged

Cat.No. : GREM2-2614H
Product Overview : Recombinant human Gremlin-2 is a N-terminus His-tagged protein that was expressed fromE. coli.MW = 17.2 kDa.
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  • Gene Information
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Cat. No. : GREM2-2614H
Description : Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mostransformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors.
Source : E.coli.
Purity : >95% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.1 ng per μg of Gremlin-2.
Form : Lyophilized with no additives.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute to 1 mg/ml with sterilized dH2O. Pipette to dissolve the protein pellet completely.
Storage : The lyophilized protein is best-stored desiccated below 0℃. Reconstituted protein should be stored at working aliquots at -20℃. Avoid freeze/thaw cycles.
Gene Name : GREM2 gremlin 2 [ Homo sapiens ]
Synonyms : GREM2; gremlin 2; PRDC; DAND3; CKTSF1B2; gremlin-2; DAN domain family member 3; protein related to DAN and Cerberus; cysteine knot superfamily 1, BMP antagonist 2; gremlin 2, cysteine knot superfamily, homolog; gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
Gene ID : 64388
mRNA Refseq : NM_022469
Protein Refseq : NP_071914
MIM : 608832
UniProt ID : Q9H772
Chromosome Location : 1q43
Pathway : Signaling by BMP
Function : cytokine activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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