||Recombinant human Gremlin-2 is a N-terminus His-tagged protein that was expressed fromE. coli.MW = 17.2 kDa.
||Gremlin (also known as Increased in High Glucose Protein 2, IHG-2, Down-regulated in Mostransformed cells protein, Drm) functions as a bone morphogenetic protein (BMP) antagonist. It acts by binding to, and forming heterodimers with BMP-2, BMP-4, BMP-7, thus preventing them from interacting with their cell surface receptors.
||>95% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.1 ng per μg of Gremlin-2.
||Lyophilized with no additives.
||Centrifuge the vial prior to opening. Reconstitute to 1 mg/ml with sterilized dH2O. Pipette to dissolve the protein pellet completely.
||The lyophilized protein is best-stored desiccated below 0℃. Reconstituted protein should be stored at working aliquots at -20℃. Avoid freeze/thaw cycles.