Recombinant Mouse Lysophospholipase 1, His-tagged
Cat.No. : | Lypla1-2813M |
Product Overview : | Recombinant mouse LYPLA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 26.8 kDa (250aa), confirmed by MALDI-TOF. |
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- Gene Information
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Cat. No. : | Lypla1-2813M |
Description : | LYPLA1 is lysophospholipase that acts on biological membranes to regulate the multifunctional lysophospholipids. This protein hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS and also has depalmitoylating activity. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MCGNNMSAPM PAVVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIKSPHIK YICPHAPVMP VTLNMNMAMP SWFDIVGLSP DSQEDESGIK QAAETVKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT ALSCWLPLRA SFSQGPINSA NRDISVLQCH GDCDPLVPLM FGSLTVERLK ALINPANVTF KIYEGMMHSS CQQEMMDVKH FIDKLLPPID |
Purity : | > 90% by SDS – PAGE. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl,1mM DTT. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | Lypla1 lysophospholipase 1 [ Mus musculus ] |
Synonyms : | Lypla1; lysophospholipase 1; Pla1a; acyl-protein thioesterase 1; APT-1; LPL-I; lysoPLA I; phospholipase 1a; OTTMUSP00000024030; OTTMUSP00000024032; OTTMUSP00000024033; lysophopholipase 1; lysophospholipase I; EC 3.1.1.5 |
Gene ID : | 18777 |
mRNA Refseq : | NM_008866 |
Protein Refseq : | NP_032892 |
UniProt ID : | P97823 |
Chromosome Location : | 1 A1; 1 |
Pathway : | Glycerophospholipid metabolism |
Function : | hydrolase activity; lysophospholipase activity |
Products Types
◆ Recombinant Protein | ||
LYPLA1-7740H | Recombinant Human LYPLA1 Protein, His-tagged | +Inquiry |
LYPLA1-4550H | Recombinant Human LYPLA1 Protein, GST-tagged | +Inquiry |
LYPLA1-3173R | Recombinant Rat LYPLA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LYPLA1-5270M | Recombinant Mouse LYPLA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LYPLA1-2426R | Recombinant Rhesus Macaque LYPLA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
LYPLA1-4589HCL | Recombinant Human LYPLA1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic mutations in LYPLA1 can lead to dysregulation of lipid metabolism and protein modification.
Altered LYPLA1 activity is linked to various diseases, including metabolic and neurodegenerative disorders.
Targeting LYPLA1 could provide new strategies for treating diseases related to lipid metabolism and protein modification.
LYPLA1 works with other lipid metabolism enzymes, coordinating lipid modification and signaling pathways.
LYPLA1, a lysophospholipase, is involved in lipid metabolism, crucial for maintaining cellular lipid balance.
LYPLA1 is involved in signal transduction processes by modulating the lipidation status of signaling proteins.
It plays a role in protein modification, particularly in depalmitoylation, affecting protein function and localization.
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