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Recombinant Mouse Lysophospholipase 1, His-tagged

Cat.No. : Lypla1-2813M
Product Overview : Recombinant mouse LYPLA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 26.8 kDa (250aa), confirmed by MALDI-TOF.
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Cat. No. : Lypla1-2813M
Description : LYPLA1 is lysophospholipase that acts on biological membranes to regulate the multifunctional lysophospholipids. This protein hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS and also has depalmitoylating activity.
Source : E.coli.
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MCGNNMSAPM PAVVPAARKA TAAVIFLHGL GDTGHGWAEA FAGIKSPHIK YICPHAPVMP VTLNMNMAMP SWFDIVGLSP DSQEDESGIK QAAETVKALI DQEVKNGIPS NRIILGGFSQ GGALSLYTAL TTQQKLAGVT ALSCWLPLRA SFSQGPINSA NRDISVLQCH GDCDPLVPLM FGSLTVERLK ALINPANVTF KIYEGMMHSS CQQEMMDVKH FIDKLLPPID
Purity : > 90% by SDS – PAGE.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl,1mM DTT.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : Lypla1 lysophospholipase 1 [ Mus musculus ]
Synonyms : Lypla1; lysophospholipase 1; Pla1a; acyl-protein thioesterase 1; APT-1; LPL-I; lysoPLA I; phospholipase 1a; OTTMUSP00000024030; OTTMUSP00000024032; OTTMUSP00000024033; lysophopholipase 1; lysophospholipase I; EC 3.1.1.5
Gene ID : 18777
mRNA Refseq : NM_008866
Protein Refseq : NP_032892
UniProt ID : P97823
Chromosome Location : 1 A1; 1
Pathway : Glycerophospholipid metabolism
Function : hydrolase activity; lysophospholipase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do genetic variations in LYPLA1 affect cell function? 05/30/2023

Genetic mutations in LYPLA1 can lead to dysregulation of lipid metabolism and protein modification.

What is the impact of altered LYPLA1 activity on disease development? 03/26/2022

Altered LYPLA1 activity is linked to various diseases, including metabolic and neurodegenerative disorders.

What potential therapeutic applications arise from targeting LYPLA1 in metabolic disorders? 10/01/2021

Targeting LYPLA1 could provide new strategies for treating diseases related to lipid metabolism and protein modification.

How does LYPLA1 interact with other enzymes in lipid metabolism? 04/28/2021

LYPLA1 works with other lipid metabolism enzymes, coordinating lipid modification and signaling pathways.

What is the primary role of LYPLA1 in cellular metabolism? 03/20/2019

LYPLA1, a lysophospholipase, is involved in lipid metabolism, crucial for maintaining cellular lipid balance.

What role does LYPLA1 play in signal transduction? 10/05/2018

LYPLA1 is involved in signal transduction processes by modulating the lipidation status of signaling proteins.

How does LYPLA1 contribute to protein modification? 03/23/2017

It plays a role in protein modification, particularly in depalmitoylation, affecting protein function and localization.

Customer Reviews (3)

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07/29/2020

    Reliable data source, highly recommended for research credibility.

    05/24/2018

      Top-notch analysis, essential for research integrity.

      11/03/2017

        Expertise shines, integral to research progress.

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