Recombinant Human Sorting Nexin 1, His-tagged

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Recombinant Human Sorting Nexin 1, His-tagged

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Cat. No. : SNX1-2800H
Product Overview : Recombinant human SNX1 protein (146-522aa), fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description : SNX1 (Sorting nexin 1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor.
Source : E.coli.
Sequences : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGGSMTV GITDPEKIGD GMNAYVAYKV TTQTSLPLFR SKQFAVKRRF SDFLGLYEKL SEKHSQNGFI VPPPPEKSLI GMTKVKVGKE DSSSAEFLEK RRAALERYLQ RIVNHPTMLQ DPDVREFLEK EELPRAVGTQ TLSGAGLLKM FNKATDAVSK MTIKMNESDI WFEEKLQEVE CEEQRLRKLH AVVETLVNHR KELALNTAQF AKSLAMLGSS EDNTALSRAL SQLAEVEEKI EQLHQEQANN DFFLLAELLS DYIRLLAIVR AAFDQRMKTW QRWQDAQATL QKKREAEARL LWANKPDKLQ QAKDEILEWE SRVTQYERDF ERISTVVRKE VIRFEKEKSK DFKNHVIKYL ETLLYSQQQL AKYWEAFLPE AKAIS.
Form : Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol.
Molecular Weight : 48.0 kDa (415aa),confirmed by MALDI-TOF.
Purity : > 90% by SDS – PAGE.
Concentration : 0.25 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDB rendering based on 2i4k. :

Gene Name : SNX1 sorting nexin 1 [ Homo sapiens ]
Synonyms :
SNX1;sorting nexin 1; sorting nexin 1A; sorting nexin-1; Vps5; SNX1A; MGC8664; HsT17379
Gene ID : 6642
mRNA Refseq : NM_003099
Protein Refseq : NP_003090
MIM : 601272
UniProt ID : Q13596
Chromosome Location : 15q22.31
Function : phosphoinositide binding; protein binding; protein transporter activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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