Recombinant Human Platelet-Derived Growth Factor-BB

• Cat.No.: PDGFB-471H
• Product Overview: RecombinantHuman Platelet-Derived Growth Factor-BB produced in Pichia Pastorishas a molecular mass of 28KD.

Specification

• Cat. No.: PDGFB-471H
• Description: Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer.
• M. W.: 28KDa
• Purity: ≥90% as determined by SDS-PAGE.
• Physical Appearance: Liquid
• Concentration: 1.2 mg/ml
• Storage Buffer: 0.11Mol/L Citric Acid / Sodium Citrate Buffer solution, PH 6.5, 0.5M NaCl.
• Storage: At 4°Cfor 6 months and -80°Cfor 2 years

Gene Information

• Gene Name: PDGFB
• Synonyms: FLJ12858; PDGF2; SIS; SSV; c-sis; Becaplermin; PDGF-2; SIS; SSV; becaplermin; c-sis; HUMANES PDGF-B GEN AUS PGEM2-PDGF-B, FLANKIERT VON 5"-ECORI UND3"-HINDIII RESTRIKTIONSSCHNITTSTELLEN;PDGFB_HUMAN;PDGF B-chain; PDGF, B chain; PDGF-B VORLAEUFERSEQUENZ; Platelet-derived growth factor B chain precursor; Platelet-derived growth factor beta polypeptide; Platelet-derived growth factor, beta polypeptide (oncogene SIS); oncogene SIS ; platelet-derived growth factor 2; platelet-derived growth factor beta; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor, B chain; v-sis platelet-derived growth factor beta polypeptide (simian sarcomaviral oncogene homolog); PDGFB
• Gene ID: 5155
• mRNA Refseq: NM_002608
• Protein Refseq: NP_002599
• MIM: 190040
• UniProt ID: P01127
• Chromosome Location: 22q12.3-q13.1; 22q13.1
• Pathway: Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma.
• Function: cell surface binding, growth factor activity, platelet-derived growth factor binding, platelet-derived growth factor receptor binding, protein binding, protein heterodimerization activity, protein homodimerization activity.