Recombinant Human NTRK1, GST-His
Cat.No. : | NTRK1-717H |
Product Overview : | Recombinant Human NTRK1, C-terminal fragment, amino acids G443-G796, N-terminally fused to GST-HIS6-Thrombin cleavage site, was expressed inSf9insect cells.MW = 69,726 Da. |
- Specification
- Gene Information
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Cat. No. : | NTRK1-717H |
Description : | TrkA is the high affinity catalytic receptor for the neurotrophin, Nerve Growth Factor, or "NGF". As such, it mediates the multiple effects of NGF, which includes neuronal differentiation and survival. |
Source : | Baculovirus infected Sf9 cells. |
Purification : | One-step affinity purification using GSH-agarose. |
Product Identity : | TRK-A was confirmed as TRK-A by by mass spectroscopy LC-ESIMS/MS (Protagen AG, Germany). |
Storage Buffer : | 50 mM HEPES-NaOH, pH 7.5; 100 mM NaCl, 5 mM DTT, 4 mM reduced glutathione, 20% glycerol. |
Concentration : | 0.133 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein). |
Specific Activity : | 29 pmol/μg×min. |
Storage : | -80°C. Avoid repeated freeze-thaw cycles! |
Gene Name : | NTRK1 neurotrophic tyrosine kinase, receptor, type 1 [ Homo sapiens ] |
Synonyms : | NTRK1; neurotrophic tyrosine kinase, receptor, type 1; MTC; TRK; TRK1; TRKA; p140-TrkA; DKFZp781I14186; Trk-A; Oncogene TRK; tyrosine kinase receptor A; high affinity nerve growth factor receptor; EC 2.7.10.1 |
Gene ID : | 4914 |
mRNA Refseq : | NM_001007792 |
Protein Refseq : | NP_001007793 |
MIM : | 191315 |
UniProt ID : | P04629 |
Chromosome Location : | 1q21-q22 |
Pathway : | Apoptosis; Endocytosis; MAPK signaling pathway; Neurotrophin signaling pathway; Pathways in cancer; Thyroid cancer; Signalling by NGF |
Function : | ATP binding; neurotrophin receptor activity; nucleotide binding; protein binding; transferase activity; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
NTRK1-2030H | Recombinant Human NTRK1 Protein, Fc/His-tagged | +Inquiry |
NTRK1-260H | Recombinant Active Human NTRK1 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
Ntrk1-4522M | Recombinant Mouse Ntrk1 Protein, Myc/DDK-tagged | +Inquiry |
NTRK1-163N | Active Recombinant Human NTRK1 Protein | +Inquiry |
NTRK1-130H | Recombinant Human NTRK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NTRK1-963CCL | Recombinant Canine NTRK1 cell lysate | +Inquiry |
NTRK1-1068RCL | Recombinant Rat NTRK1 cell lysate | +Inquiry |
NTRK1-2147HCL | Recombinant Human NTRK1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1627 | TrkA Functional Assay Kit | +Inquiry |
Kit-1546 | U2OS TrkA Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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