"MAPK13" Related Products


Recombinant Human Mitogen-activated Protein Kinase 13

Cat. No. : MAPK13-737H
Product Overview : Recombinant Human p38-delta, full length, amino acids M1-L365, activated, untagged, was expressed inE.coli.MW = 42,430 Da.
Description : P38δ (SAPK4) is a member of the p38 MAPK family and is activated by chemical and environmental stresses as well as by proinflammatory cytokines. P38δ has a TGY dual phosphorylation motif and is activated in response to cellular stresses and proinflammatory cytokines. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Source : E.coli.
Purification : GST-Affinity Chromatography.
Activation : with MKK6-S207D/T211D.
Product Identity : p38-delta was confirmed as p38-delta by mass spectroscopy LCESI-MS/MS.
Storage Buffer : 50 mM HEPES pH 7.5, 100 mM NaCl, 5 mM DTT, 20% glycerol.
Concentration : 0.468 μg/μl (Bradford method using BSA [Sigma, cat# A-7638, Lot 79H7641] as standard protein).
Specific Activity : 481 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : MAPK13 mitogen-activated protein kinase 13 [ Homo sapiens ]
Synonyms : MAPK13; mitogen-activated protein kinase 13; SAPK4; PRKM13; MGC99536; p38delta; stress-activated protein kinase 4; mitogen-activated protein kinase p38 delta; mitogen activated protein kinase 13; EC
Gene ID : 5603
mRNA Refseq : NM_002754
Protein Refseq : NP_002745
MIM : 602899
UniProt ID : O15264
Chromosome Location : 6p21.31
Pathway : Amyotrophic lateral sclerosis (ALS); Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; GnRH signaling pathway; Leukocyte transendothelial migration; MAPK signaling pathway; Neurotrophin signaling pathway; RIG-I-like receptor signaling pathway; T cell receptor signaling pathway; Toll-like receptor signaling pathway; VEGF signaling pathway; Signalling by NGF
Function : ATP binding; MAP kinase activity; MAP kinase kinase activity; MP kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity; transferase activity

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