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Recombinant Mouse Phospholipase A2, Group XIIA

Cat.No. : Pla2g12a-712M
Product Overview : Recombinant Mouse Phospholipase A2, Group XIIA is produced inEscherichia coli.MW=65 kDa.
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Cat. No. : Pla2g12a-712M
Description : Group XIIA secretory phospholipase A2 is an enzyme that in humans is encoded by the PLA2G12A gene.
Source : E.coli.
Purity : >85% (SDS-PAGE).
Reconstitution : Reconstitute the vial with deionized water.
Solubility : H2O: soluble0.5 mg/mL. Tris pH 8.0: easily soluble.
Storage : −20°C. Shipped in wet ice.
Gene Name : Pla2g12a phospholipase A2, group XIIA [ Mus musculus ]
Synonyms :
Pla2g12a; phospholipase A2, group XIIA; GXII; Rossy; Pla2g12; mGXII-1; MGC58884; mGXII-1-PLA2; 2310004B05Rik; GXII sPLA2; group XII-1 phospholipase A2; group XIIA secreted phospholipase A2; group XIIA secretory phospholipase A2; phosphatidylcholine 2-acylhydrolase 12A; sPLA2-XII; EC 3.1.1.4
Gene ID : 66350
mRNA Refseq : NM_023196
Protein Refseq : NP_075685
UniProt ID : Q9EPR2
Chromosome Location : 3 H1;3
Pathway : Arachidonic acid metabolism; Ether lipid metabolism; Fc epsilon RI signaling pathway; Glycerophospholipid metabolism; GnRH signaling pathway; Linoleic acid metabolism; Long-term depression; MAPK signaling pathway; Metabolic pathways; VEGF signaling pathway; Vascular smooth muscle contraction; alpha-Linolenic acid metabolism
Function : calcium ion binding; calcium-dependent phospholipase A2 activity; hydrolase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does PLA2G12A contribute to cell signaling pathways? 12/15/2022

PLA2G12A-generated lipid mediators can act as signaling molecules, influencing various cellular processes and pathways.

Can PLA2G12A be a therapeutic target for cancer treatment? 03/22/2022

Investigations are underway to explore the role of PLA2G12A in cancer progression, with the goal of identifying therapeutic strategies to target this protein.

How does PLA2G12A contribute to inflammatory responses? 01/17/2019

PLA2G12A is involved in the generation of lipid mediators, such as eicosanoids, which play a role in inflammation and immune responses.

Can the measurement of PLA2G12A levels be used as a diagnostic marker? 01/16/2019

Studies suggest that alterations in PLA2G12A expression or activity may serve as potential diagnostic markers for certain diseases, although more research is needed.

Are there any ongoing clinical trials targeting PLA2G12A? 03/23/2016

Information on current clinical trials targeting PLA2G12A can be obtained from databases like ClinicalTrials.gov, indicating the evolving interest in its therapeutic potential.

Customer Reviews (3)

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Reviews
10/30/2017

    the manufacturer of the PLA2G12A protein plays a vital role in supporting my research endeavors.

    03/10/2017

      the manufacturer's commitment to ongoing innovation ensures that I have access to the most advanced and updated versions of the PLA2G12A protein.

      06/09/2016

        They proactively monitor scientific advancements and customer feedback to continually refine and improve the performance of the protein.

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