| Cat. No. : | NMNAT3-639H |
| Product Overview : | Recombinant Human NMNAT3 is produced inE.coliand fused at the N-terminus to a His-tag. MW=30.3kDa. |
| Description : | The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD. |
| Source : | E.coli. |
| Purity : | ≥95% (SDS-PAGE). |
| Formulation : | Liquid. In 50mM sodium phosphate, pH 8.0, containing 300mM sodium chloride, 1mM DTT and 10% glycerol. |
| Application : | Well suited for the synthesis of NAD analogs due to lower substrate selectivity compared to NMNAT1. |
| Storage And Stability : | -20°C. Stable for at least 3 months after receipt when stored at -20°C. Avoid freeze/thaw cycles. |
| Gene Name : | NMNAT3 nicotinamide nucleotide adenylyltransferase 3 [ Homo sapiens ] |
| Synonyms : | NMNAT3; nicotinamide nucleotide adenylyltransferase 3; PNAT3; EC 2.7.7.1; EC 2.7.7.18 |
| Gene ID : | 349565 |
| mRNA Refseq : | NM_178177 |
| Protein Refseq : | NP_835471 |
| MIM : | 608702 |
| UniProt ID : | Q96T66 |
| Chromosome Location : | 3q23 |
| Pathway : | Metabolic pathways; Nicotinate and nicotinamide metabolism; Metabolism of vitamins and cofactors |
| Function : | ATP binding; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; nucleotide binding; nucleotidyltransferase activity; protein binding; transferase activity |
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Download Datasheet
See All NMNAT3 Products
Download Datasheet