Kit-0326
Optional Service: Optional requirements on this protein
Product Overview :
EphA2 Kinase (Human) Assay/Inhibitor Screening Assay Kit is a single-site, non-quantitative immunoassay for kinase activity of recombinant catalytic domain of EphA2 kinase. Plates are pre-coated with a newly designed "Tyrosine kinase-substrate-1", which can be easily phosphorylated by recombinant catalytic domain of EphA2 kinase. The detector antibody is PY-39, an antibody that specifically detects the phosphotyrosine residue on "Tyrosine kinase-substrate-1".
Description :
The EphA2 receptor tyrosine kinase belongs to the Eph receptor family. The Eph family contains at least 14 members that are type I transmembrane glycoproteins. Upon cell-cell contact, Eph receptors interact with their ligands called ephrins. Glycosylphosphatidyl inositol-linked ephrin-A ligands bind to EphA receptors and transmembrane ephrin-B ligands bind to EphB receptors. Eph-ephrin signaling mediates contact-dependent cell interactions involved in the spatial organization of neurons and neural crest cells, embryogenesis, tissue patterning, and blood vessels formation.
Applications :
1) Screening inhibitors or activators of recombinant catalytic domain of EphA2 Kinase.2) Detecting the effects of pharmacological agents on recombinant catalytic domain of EphA2 Kinase.
Storage :
Upon receipt store all other components at 4°C; Do not expose reagents to excessive light
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.