Active GMP Recombinant Human TGFB3 protein, Fc-tagged
Cat.No. : | TGFB3-193HG |
Product Overview : | GMP Recombinant Human TGFB3 protein(NP_003230)(375 aa), fused with Fc Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Bio-activity : | ED50 is determined by the ability of TGF-β3, which can inhibit the proliferation ability of mouse IL-4 dependent mouse HT-2 cells, and its value is <=0.1 ng/ml. |
Molecular Mass : | Recombinant Human TGF-β3 contains 375 aa. It has a predicted MW of 42.1 kDa. |
Protein length : | DNA sequence encoding Human TGF-β3(CAA33024.1) was expressed with Fc tag at the C-terminal. |
Endotoxin : | <=0.01EU/ug |
Purity : | >=95% by SDS-PAGE and HPLC |
Storage : | The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TGFB3 transforming growth factor, beta 3 [ Homo sapiens ] |
Official Symbol : | TGFB3 |
Synonyms : | TGFB3; transforming growth factor, beta 3; transforming growth factor beta-3; TGF-beta-3; ARVD; TGF-beta3; FLJ16571; |
Gene ID : | 7043 |
mRNA Refseq : | NM_003239 |
Protein Refseq : | NP_003230 |
MIM : | 190230 |
UniProt ID : | P10600 |
Products Types
◆ Recombinant Protein | ||
TGFB3-2764H | Recombinant Human TGFB3 Protein, His-tagged | +Inquiry |
TGFB3-105H | Active Recombinant Human TGFB3 Protein | +Inquiry |
Tgfb3-6390M | Recombinant Mouse Tgfb3 Protein, Myc/DDK-tagged | +Inquiry |
TGFB3-38H | Recombinant Human TGFB3 Protein | +Inquiry |
TGFB3-288H | Active Recombinant Human TGFB3 Protein (Ala301-Ser412), C-His tagged, Animal-free, Carrier-free | +Inquiry |
◆ Lysates | ||
TGFB3-1118HCL | Recombinant Human TGFB3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionCurrently, researchers are exploring treatments that target TGFB3. Several drugs and antibodies have shown potential efficacy against TGFB3 and are being used in clinical trials for the treatment of the disease.
TGFB3 can regulate cell proliferation by activating multiple signaling pathways, such as the Smad signaling pathway and non-Smad signaling pathway. It can promote the progression of the cell cycle or inhibit cell proliferation, depending on the cell type and context.
TGFB3 protein can be used as a biomarker to assist the clinical diagnosis of a variety of diseases, such as congenital developmental abnormalities, inflammatory diseases and fibrotic diseases. Measuring TGFB3 protein levels can provide an indicator of early diagnosis and prognostic assessment of disease.
Mutations in TGFB3 have been found to be associated with inherited connective tissue diseases such as Loeys-Dietz syndrome and Marfan syndrome.
In pulmonary fibrosis, the expression of TGFB3 is elevated and is involved in the development of pulmonary fibrosis. Due to its important role in the pathological process, inhibition of the TGFB3 signaling pathway may be a potential strategy for the treatment of pulmonary fibrosis.
TGFB3 plays an important regulatory role in the immune system. It can influence the immune response through the proliferation, differentiation, and functional regulation of immune cells.
Customer Reviews (3)
Write a reviewReproducibility is very good, and the results are very consistent in each experiment or application, making it ideal for experiments or applications that require a high degree of reproducibility.
Their recombinant proteins are very soluble and can be easily dissolved in various buffers.
Catalytic activity of this protein is very high, which can greatly reduce the time and energy required for chemical reactions and has high economic value.
Ask a Question for All TGFB3 Products
Required fields are marked with *
My Review for All TGFB3 Products
Required fields are marked with *
Inquiry Basket