Human AP2S1 Knockdown Cell Lysate

• Cat.No.: AP2S1-041HKCL
• Product Overview: WB-validated AP2S1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 17 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg AP2S1 KD HeLa cell lysate
• Protein Pathways: Endocytosis, Huntington's disease
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: AP2S1 adaptor-related protein complex 2, sigma 1 subunit [ Homo sapiens (human) ]
• Official Symbol: AP2S1
• Synonyms: AP2S1; adaptor-related protein complex 2, sigma 1 subunit; CLAPS2; AP-2 complex subunit sigma; sigma2-adaptin; HA2 17 kDa subunit; clathrin coat assembly protein AP17; clathrin coat-associated protein AP17; clathrin assembly protein 2 small chain; adaptor protein complex AP-2 subunit sigma; plasma membrane adaptor AP-2 17 kDa protein; adapter-related protein complex 2 sigma subunit; clathrin-associated/assembly/adaptor protein, small 2 (17kD); AP17; AP17-DELTA
• Gene ID: 1175
• mRNA Refseq: NM_004069
• Protein Refseq: NP_004060
• MIM: 602242
• UniProt ID: P53680