Human GARS1 Knockdown Cell Lysate

• Cat.No.: GARS1-171HKCL
• Product Overview: WB-validated GARS1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: #N/A
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg GARS1 KD HeLa cell lysate
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: GARS1 glycyl-tRNA synthetase 1 [ Homo sapiens (human) ]
• Official Symbol: GARS1
• Synonyms: GARS1; glycyl-tRNA synthetase 1; GARS; HMN5; CMT2D; DSMAV; GlyRS; HMN5A; HMND5; SMAD1; SMAJI; glycine--tRNA ligase; AP-4-A synthetase; Charcot-Marie-Tooth neuropathy 2D; Charcot-Marie-Tooth neuropathy, neuronal type, D; ap4A synthetase; diadenosine tetraphosphate synthetase; EC 6.1.1.14
• Gene ID: 2617
• mRNA Refseq: NM_002047
• Protein Refseq: NP_002038
• MIM: 600287
• UniProt ID: P41250