Human LGI1 Knockdown Cell Lysate

• Cat.No.: LGI1-365HKCL
• Product Overview: WB-validated LGI1 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 64 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg LGI1 KD HeLa cell lysate
• Protein Families: Druggable Genome, Secreted Protein
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: LGI1 leucine-rich, glioma inactivated 1 [ Homo sapiens (human) ]
• Official Symbol: LGI1
• Synonyms: LGI1; leucine-rich, glioma inactivated 1; epilepsy, partial, EPT; leucine-rich glioma-inactivated protein 1; EPITEMPIN; ETL1; IB1099; epitempin-1; EPT; ADLTE; ADPAEF
• Gene ID: 9211
• mRNA Refseq: NM_005097
• Protein Refseq: NP_005088
• MIM: 604619
• UniProt ID: O95970