Human LMNB2 Knockdown Cell Lysate

• Cat.No.: LMNB2-228HKCL
• Product Overview: WB-validated LMNB2 Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 68 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg LMNB2 KD HeLa cell lysate
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: LMNB2 lamin B2 [ Homo sapiens (human) ]
• Official Symbol: LMNB2
• Synonyms: LMNB2; lamin B2; LMN2; lamin-B2; LAMB2; MGC2721
• Gene ID: 84823
• mRNA Refseq: NM_032737
• Protein Refseq: NP_116126
• MIM: 150341
• UniProt ID: Q03252