Interleukin-2 with its alpha Receptor

Cat.No. : CBCRY33
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Cat. No. : CBCRY33
Background : Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits.
Protein Classification : Immune System
Structure Weight : 40207.9 Da
Polymer : 1
Molecule : Interleukin-2
Chain Length : 133 amino acids
PDB ID : 1Z92
MMDB ID : 33820
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.80 Å
Reference : Rickert, M., Wang, X., Boulanger, M.J., Goriatcheva, N., Garcia, K.C. (2005) The structure of interleukin-2 complexed with its alpha receptor. Science 308: 1477-1480
Gene Name : IL2
Synonyms : IL-2; TCGF; lymphokine; T cell growth factor; aldesleukin; interleukin-2; involved in regulation of T-cell clonal expansion; Aldesleukin
UniProt ID : P60568
Chromosome Location : 4q26-q27
Function : cytokine activity; interleukin-2 receptor binding; protein binding; growth factor activity; kinase activator activity
Gene ID : 3558

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Q&As (6)

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Is there any adverse effect of IL2RA combined with other drugs? 12/10/2022

The combination of IL2RA and other drugs may produce nausea, vomiting, rash and other adverse reactions, should be monitored.

How often is IL2RA used? 01/11/2022

The frequency of use of IL2RA depends on the specific situation of the patient, and is generally used 1-3 times per week.

Whether there is an effect of IL2RA? 12/17/2021

IL2RA, in the right dosage and frequency of use, can significantly relieve symptoms of diseases such as autoimmune diseases and organ transplant rejection.

Can IL2RA treat cancer? 05/18/2021

Can assist in the treatment of some types of malignant tumors, but it is not a complete cure for cancer.

How effective is IL2RA treatment? 04/07/2020

The effective rate of IL2RA therapy depends on many factors such as the type of disease, the patient's condition and the treatment regimen, and the effective rate is generally between 50% and 90%.

What are the indications for IL2RA? 01/09/2020

Indications of IL2RA include a variety of autoimmune diseases, organ transplant rejection and malignant tumors.

Customer Reviews (3)

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Reviews
09/29/2022

    Security is very high and can be used with confidence.

    06/05/2021

      Structure is very stable and not prone to mutation.

      03/14/2019

        The amount of expression is very high and can be easily detected.

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