Interleukin-2 with its alpha Receptor CBCRY33

Interleukin-2 with its alpha Receptor


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Interleukin-2 with its alpha Receptor

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Cat.No. : CBCRY33 Optional Service: Optional requirements on this protein
Background : Interleukin-2 (IL-2) is an immunoregulatory cytokine that binds sequentially to the alpha (IL-2Ralpha), beta (IL-2Rbeta), and common gamma chain (gammac) receptor subunits.
Protein Classification : Immune System
Structure Weight : 40207.9 Da
Polymer : 1
Molecule : Interleukin-2
Chain Length : 133 amino acids
PDB ID : 1Z92
MMDB ID : 33820
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.80 Å
Reference : Rickert, M., Wang, X., Boulanger, M.J., Goriatcheva, N., Garcia, K.C. (2005) The structure of interleukin-2 complexed with its alpha receptor. Science 308: 1477-1480
Gene Name : IL2
Synonyms : IL-2; TCGF; lymphokine; T cell growth factor; aldesleukin; interleukin-2; involved in regulation of T-cell clonal expansion; Aldesleukin
UniProt ID : P60568
Chromosome Location : 4q26-q27
Function : cytokine activity; interleukin-2 receptor binding; protein binding; growth factor activity; kinase activator activity
Gene ID : 3558
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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