Mouse Anti-IL1RN Monoclonal Antibody
| Cat.No. : | DMABT-H18692 |
| Product Overview : | Mouse Anti-IL1RN Monoclonal Antibody |
- Specification
- Gene Information
- Related Products
| Antigen Description : | Interleukin-1 receptor antagonist (IL-1RA) is composed of three isoforms, one secreted (sIL-1Ralpha/IL-1Ralpha1), two intracellular (IL-1Ralpha2/IL-1Ralpha3) and produced by monocytes, tissue macrophages, Langerhans cells, dendritic cells, T and B cells, natural killer (NK) cells, large granular lymphocytes (LGL), vascular endothelium, smooth muscle, fibroblasts, thymic epithelia, astrocytes, microglia, glioma cells, keratinocytes, and chondrocytes. It is upregulated by IL-1beta, IL-4, IL-6 and downregulated by glucocorticoids. |
| Target : | IL1RN |
| Immunogen : | Recombinant human IL-1 receptor antagonist |
| Host : | Mouse |
| Isotype : | IgG1 |
| species : | Human |
| Clone : | KL2SB-2 |
| Conjugation : | N/A |
| Applications : | ELISA |
| Preparation : | The antibody was purified by affinity chromatography. |
| Usage recommendation : | Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 4-6 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application. |
| Concentration : | 0.5 mg/ml |
| Storage : | The antibody solution should be stored undiluted at 4 °C. |
| Size : | 50 μg;500 μg |
| Gene Name : | IL1RN interleukin2receptor antagonist [ Homo sapiens ] |
| Official Symbol : | IL1RN |
| Synonyms : | IL1RN; interleukin2receptor antagonist; interleukin-1 receptor antagonist protein; ICIL 1RA; IL 1RN; IL1F3; IL1RA; interleukin2receptor antagonist protein; intracellular interleukin2receptor antagonist; IRAP; MGC10430; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); DIRA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; |
| Gene ID : | 3557 |
| mRNA Refseq : | NM_000577 |
| Protein Refseq : | NP_000568 |
| MIM : | 147679 |
| UniProt ID : | P18510 |
| Chromosome Location : | 2q14.2 |
| Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem; Signaling by Interleukins, organism-specific biosystem; |
| Function : | interleukin-1 Type I receptor antagonist activity; interleukin-1 Type II receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor antagonist activity; interleukin-1 receptor binding; interleukin-1, Type I receptor binding; interleukin-1, Type II receptor binding; |
Products Types
| ◆ Recombinant Protein | ||
| Il1rn-168M | Recombinant Active Mouse IL1RN Protein, His-tagged(C-ter) | +Inquiry |
| IL1RN-362C | Recombinant Cynomolgus Monkey IL1RN Protein, His (Fc)-Avi-tagged | +Inquiry |
| IL1RN-1819H | Recombinant Human IL1RN Protein, MYC/DDK-tagged | +Inquiry |
| IL1RN-2692R | Recombinant Rat IL1RN Protein, His (Fc)-Avi-tagged | +Inquiry |
| IL1RN-167H | Recombinant Active Human IL1RN Protein, His-tagged(C-ter) | +Inquiry |
| ◆ Lysates | ||
| IL1RN-2912HCL | Recombinant Human IL1RN cell lysate | +Inquiry |
| IL1RN-1375RCL | Recombinant Rat IL1RN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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