| Description : |
Jacalin is a lectin composed of four subunits of approximately 16 kDa each. This lectin appears to bind only O-glycosidically linked oligosaccharides, preferring the structure galactosyl (β-1,3) N-acetylgalactosamine. This structure (the T-antigen) is the oligosaccharide to which peanut agglutinin (PNA) binds. However, unlike PNA, Jacalin will bind a mono- or disialylated form of this structure. This lectin has been used to purify human IgA. The specificity of this lectin also affords the opportunity to localize or isolate glycoproteins with O-glycosidically linked oligosaccharide side chains. |
| Source : |
Artocarpus integrifolia |
| Species : |
Artocarpus integrifolia |
| Bio-activity : |
Inhibiting/Eluting Sugar: 800 mM galactose or 100 mM melibiose |
| Molecular Mass : |
66 kDa |
| Applications : |
Glycobiology, Mitogenic Stimulation |
| Usage : |
Although many buffers can be employed for reconstituting and diluting this lectin, 10 mM HEPES buffered saline, pH 8.5, 0.1 mM Ca2+ is recommended. For preserving solutions, stored at 4 centigrade, 0.08% sodium azide can be used. |
| Storage : |
Refrigerate |
| Synonyms : |
Lectin; Jacalin |
