Native Bovine MFGE8, Fluoresence-labeled
Cat.No. : | MFGE8-8518B |
Product Overview : | Native Bovine Lactadherin is purified from un-pasteurized bovine milk. |
- Specification
- Gene Information
- Related Products
Description : | Lactadherin is a widely distributed glycoprotein (~ 50 kDa), which was originally characterized due to its association with milk fat/lipid globule membranes. Synonymous names are PAS-6/7, bovine-associated mucoprotein, BA-46, P47, and MFG-E8. Structural hallmarks of lactadherin are the presence of two epidermal growth factor (EGF) homology domains (with an RGD peptide motif in the second EGF domain), and two C domains sharing homology with the discoidin family of lectin domains including the phospholipid-binding domains of blood clotting factors V and VIII. Lactadherin shows preferential binding to phosphatidylserine (L-form) in a calcium independent manner. Purified lactadherin functions as an anticoagulant by blocking phosphatidylserine-containing membrane sites for blood coagulation proteins. Fluoresence-labeled lactadherin functions as a sensitive probe for exposed phosphatidylserine on nucleated cells and on stimulated platelets. Lactadherin will bind to membranes that have phosphatidylserine content below the threshold for annexin V binding. |
Source : | Bovine |
Species : | Bovine |
Form : | 70 mM Sodium Phosphate, pH 7.0 |
Molecular Mass : | 52 kDa and 47 kDa (glycosylation variants, PAS-6 and PAS-7 respectively) |
Purity : | >95% by SDS-PAGE (both) |
Storage : | -70℃ |
Gene Name : | MFGE8 milk fat globule-EGF factor 8 protein [ Bos taurus ] |
Official Symbol : | MFGE8 |
Synonyms : | MFGE8; BP47; MFG-E8; MFGM; MGP57/53; PAS-6/PAS-7 glycoprotein; SED1; components 15/16; lactadherin; sperm surface protein SP47 |
Gene ID : | 281913 |
mRNA Refseq : | NM_176610.1 |
Protein Refseq : | NP_788783.1 |
UniProt ID : | Q95114 |
Products Types
◆ Recombinant Protein | ||
MFGE8-3466H | Recombinant Human MFGE8 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mfge8-4056M | Recombinant Mouse Mfge8 Protein, Myc/DDK-tagged | +Inquiry |
MFGE8-4385H | Recombinant Human MFGE8 Protein, GST-tagged | +Inquiry |
MFGE8-445H | Recombinant Human MFGE8 Protein (Met1-Cys387), His-AVI-tagged, Biotinylated | +Inquiry |
MFGE8-1242H | Recombinant Human MFGE8 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
MFGE8-289B | Native MFG-E8 | +Inquiry |
MFGE8-288B | Native Bovine Lactadherin | +Inquiry |
◆ Lysates | ||
MFGE8-422HCL | Recombinant Human MFGE8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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