Description : |
GSL I is a family of glycoproteins with molecular weights of approximately 114 kDa. There are two types of subunits, termed A and B , with slightly different molecular weights. These subunits combine to form tetrameric structures, resulting in five isolectins. The A -rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for α-N-acetylgalactosamine residues, while the B -rich lectin preferentially agglutinates blood group B cells and is specific for α-galactose residues. This GSL I is a mixture of the five isolectins. GSL I has been reported to bind several glycoproteins including laminin. |
Source : |
Griffonia Simplicifolia |
Species : |
Griffonia Simplicifolia |
Form : |
10 mM HEPES, pH 7.5, 0.15 M NaCl, 0.08% sodium azide, 0.1 mM Ca2+. |
Bio-activity : |
Inhibiting/Eluting Sugar: mixture of 200 mM galactose/200 mM N-acetylgalactosamine. Carbohydrate-Binding Specificity: Galactose, N-Acetylgalactosamine. |
Molecular Mass : |
114 kDa |
Applications : |
Immunohistochemistry / Immunocytochemistry, Immunofluorescence, Blotting Applications, Elispot, ELISAs |
Usage : |
For most applications we recommend a freshly prepared working solution of 5-20 µg/ml. |
Storage : |
Refrigerate; for long term storage, aliquots may be stored frozen. |
Concentration : |
2 mg/ml |
Synonyms : |
Lectin; GSL I; BSL I |
UniProt ID : |
Q8W1R6 |